ZBTB25 and HSBP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZBTB25	HSBP1
Description		zinc finger and BTB domain containing 25	heat shock factor binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Nucleus Nucleoplasm Cytosol Cytoskeleton Axon Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Axonal Transport Of Mitochondrion Endodermal Cell Differentiation Cellular Heat Acclimation
Pathways			HSF1 activation Attenuation phase HSF1-dependent transactivation
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 32888494 27863252)	Lead levels ( 26025379) Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		34 interacting genes: APIP COIL CRACR2B CYP2J2 CYSRT1 DDIT3 FCGR3A FHL2 HCLS1 HOMEZ HSBP1 KCTD1 KCTD9 KRTAP10-8 KRTAP17-1 KXD1 LZTS2 MAPK9 MDFI PCBD1 PNMA5 SEPHS1 SORBS3 SSX3 SUMO2 TBC1D5 TNIP1 TRAF2 TRAF6 TSSK3 VCP VMAC ZBTB1 ZBTB2	25 interacting genes: BLOC1S5 BRK1 CCHCR1 CD1B CYSRT1 GORASP2 HSF1 HSPA1A KIAA1217 KIFC3 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 LNX1 MPHOSPH6 MPP7 NOTCH2NLA RPL13 SDCBP SDCBP2 SDR42E1 WASHC1 WASHC3 ZBTB25
Entrez ID		7597	3281
HPRD ID		01926	05185
Ensembl ID		ENSG00000089775	ENSG00000230989
Uniprot IDs		G3V2K3 P24278	O75506
PDB IDs			3CI9
Enriched GO Terms of Interacting Partners?
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