ZSCAN21 and ZKSCAN4

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		ZSCAN21	ZKSCAN4
Description		zinc finger and SCAN domain containing 21	zinc finger with KRAB and SCAN domains 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Male Meiosis I Spermatogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Basal metabolic rate ( 31453325) Basal metabolic rate variance ( 31453325) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278) Schizophrenia ( 30285260) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		31 interacting genes: APP BRCA1 CAVIN1 CEP70 CLK2 DVL3 GRAP2 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 OGT PICK1 SCAND1 TRIM41 ZKSCAN4 ZKSCAN7 ZNF213 ZNF24 ZNF396 ZNF446 ZNF483 ZNF496 ZNF837 ZSCAN12 ZSCAN22 ZSCAN23 ZSCAN32	23 interacting genes: CABP5 IL36RN LXN MDM4 MEOX2 OGT OSGIN1 PGBD1 PSMA6 SCAND1 TIAM1 TRIM39 ZKSCAN7 ZNF24 ZNF397 ZNF446 ZNF483 ZNF496 ZSCAN20 ZSCAN21 ZSCAN22 ZSCAN30 ZSCAN32
Entrez ID		7589	387032
HPRD ID		03162	15768
Ensembl ID		ENSG00000166529	ENSG00000187626
Uniprot IDs		Q9Y5A6	A0A0S2Z658 B7Z7H3 Q969J2
PDB IDs
Enriched GO Terms of Interacting Partners?
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