WIPF1 and RER1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		WIPF1	RER1
Description		WAS/WASL interacting protein family member 1	retention in endoplasmic reticulum sorting receptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytosol Actin Filament Actin Cytoskeleton Cytoplasmic Vesicle	Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Plasma Membrane Cell Surface Integral Component Of Golgi Membrane
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding	Molecular_function Protein Binding Acetylcholine Receptor Binding
	Biological Process	Actin Polymerization Or Depolymerization Actin Filament-based Movement Protein-containing Complex Assembly	Protein Retention In ER Lumen Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs CDC42 GTPase cycle RAC1 GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494) Pulse pressure ( 27841878) Resting heart rate ( 27798624) Systolic blood pressure ( 27841878) Urate levels (BMI interaction) ( 25811787)	Body mass index ( 26426971) Metabolite levels ( 23823483) Serum alkaline phosphatase levels ( 33547301) Vitamin C levels ( 33203707)
Interacting Genes		27 interacting genes: ABI2 ACTC1 ACTG1 ALAS1 APBB1 CACNG2 CDC42 CRKL CTTN FASTK GRB2 HCK HLCS HOMER3 ITSN2 NCK1 NCK2 PRKCQ PRPF40A RER1 SEC24C SH3RF1 WAS WASL WBP4 WWP2 ZAP70	7 interacting genes: GCH1 HAP1 IMMT SCAND1 SH3GL3 SYT16 WIPF1
Entrez ID		7456	11079
HPRD ID		03835	17967
Ensembl ID		ENSG00000115935	ENSG00000157916
Uniprot IDs		A0A140VJZ9 O43516 Q2YDC4	O15258 Q5T094
PDB IDs		2A41
Enriched GO Terms of Interacting Partners?
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