WARS1 and DCAF13

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		WARS1	DCAF13
Description		tryptophanyl-tRNA synthetase 1	DDB1 and CUL4 associated factor 13
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Protein-containing Complex Extracellular Exosome	Nucleoplasm Nucleolus Centrosome Cytosol Cell Junction Small-subunit Processome Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Tryptophan-tRNA Ligase Activity Protein Binding ATP Binding Kinase Inhibitor Activity Protein Kinase Binding Protein Domain Specific Binding Protein Homodimerization Activity	RNA Binding Protein Binding Estrogen Receptor Binding
	Biological Process	Angiogenesis Negative Regulation Of Protein Phosphorylation Translation Tryptophanyl-tRNA Aminoacylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Regulation Of Protein ADP-ribosylation Positive Regulation Of Protein-containing Complex Assembly Regulation Of Angiogenesis	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Protein Ubiquitination
Pathways		Cytosolic tRNA aminoacylation	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol Neddylation
Drugs		Tryptophan Tryptophanyl-5'amp Tryptophanamide
Diseases
GWAS
Interacting Genes		11 interacting genes: APP CDK2AP2 DCAF13 DNMT3B EEF1A1 LIG4 LINC01554 MDH2 OGT TERF1 UBC	4 interacting genes: PABPC1 PTEN TK1 WARS1
Entrez ID		7453	25879
HPRD ID		01845	08528
Ensembl ID		ENSG00000140105	ENSG00000164934
Uniprot IDs		A0A024R6K8 P23381	A0A087WT20 Q9NV06
PDB IDs		1O5T 1R6T 1R6U 1ULH 2AKE 2AZX 2DR2 2QUH 2QUI 2QUJ 2QUK 5UJI 5UJJ
Enriched GO Terms of Interacting Partners?
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