UQCRC2 and UQCRC1

Number of citations of the paper that reports this interaction (PubMedID 11073949)
17

Data Source:
HPRD (in vitro)

		UQCRC2	UQCRC1
Description		ubiquinol-cytochrome c reductase core protein 2	ubiquinol-cytochrome c reductase core protein 1
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Mitochondrial Respiratory Chain Complex IV	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respirasome Mitochondrial Respiratory Chain Complex III
	Molecular Function	Metalloendopeptidase Activity Protein Binding Protein-containing Complex Binding Metal Ion Binding	Protein Binding Ubiquinol-cytochrome-c Reductase Activity Ubiquitin Protein Ligase Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Oxidative Phosphorylation Proteolysis Aerobic Respiration Response To Xenobiotic Stimulus	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration Response To Activity Response To Alkaloid Proton Transmembrane Transport
Pathways		Respiratory electron transport	Respiratory electron transport
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2	2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Myxothiazol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Metabolite levels ( 23823483) Platelet count ( 32888494) Plateletcrit ( 32888494) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		4 interacting genes: CACNA1A EPHB1 RTN4 UQCRC1	11 interacting genes: BDKRB1 CYCS ERCC6 GPX1 HNRNPD KRAS NLGN3 OGT RTN4 TRIM63 UQCRC2
Entrez ID		7385	7384
HPRD ID		01876	01875
Ensembl ID		ENSG00000140740	ENSG00000010256
Uniprot IDs		P22695	P31930
PDB IDs		5XTE 5XTH 5XTI	5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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