UGP2 and GLRX3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		UGP2	GLRX3
Description		UDP-glucose pyrophosphorylase 2	glutaredoxin 3
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Nucleus Cytosol Cell Cortex Z Disc Dendrite
	Molecular Function	UTP:glucose-1-phosphate Uridylyltransferase Activity Protein Binding Glucose Binding Pyrimidine Ribonucleotide Binding Identical Protein Binding Metal Ion Binding	RNA Binding Protein Kinase C Binding Protein Binding Identical Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding Glutathione Oxidoreductase Activity
	Biological Process	Glycogen Metabolic Process Glycogen Biosynthetic Process UDP-glucose Metabolic Process Brain Development Glucose 1-phosphate Metabolic Process	Regulation Of The Force Of Heart Contraction Cellular Iron Ion Homeostasis Negative Regulation Of Cardiac Muscle Hypertrophy [2Fe-2S] Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer
Pathways		Formation of the active cofactor, UDP-glucuronate Glycogen synthesis	Iron uptake and transport
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Smoking initiation (ever regular vs never regular) ( 30679032) Systolic blood pressure ( 26969751)	Alcohol dependence ( 26365420) Colorectal cancer ( 34062886) Copper levels ( 26025379) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) HIV-1 susceptibility ( 21160409) Mean corpuscular volume ( 32888494) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Sleep end time ( 33075057) Triglyceride levels x short total sleep time interaction (1df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		7 interacting genes: ABCA1 ARIH2 CBS GLRX3 PCBP1 PLEKHF2 TTN	101 interacting genes: ADAMTSL3 ADAMTSL4 ALKBH3 BCL6 BOLA1 BOLA2 BOLA2B BOLA3 CA9 CBLB CCHCR1 CERCAM CGGBP1 CIAPIN1 COL8A1 DANCR EFEMP2 ERBB2 FAM118A FRA10AC1 GATA1 GMCL1 GNG13 GRN HEXD HSD3B7 IHO1 IKZF1 IL10 IRX6 KLHDC9 KRT31 KRT38 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP13-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-3 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE2D LNX1 LNX2 LRIG1 MAP3K3 MAPK6 MAPKBP1 MDFI METAP1 MOXD1 NADK NOTCH2NLA NTF4 OLFM3 PCSK5 PFDN5 PLEKHG4B PLSCR1 PRKCQ PRKCZ PRKD2 RCOR3 RECK REL RGS20 SMARCC1 SOX7 STAU1 STRA6 TCF4 TCL1B TLE5 TMEM25 TRAF1 TRIM36 TRIM42 UGP2 ZBTB44 ZNF124 ZNF148 ZNF23 ZNF426 ZNF490 ZNF512B ZNF544 ZNF774
Entrez ID		7360	10539
HPRD ID		08934	10153
Ensembl ID		ENSG00000169764	ENSG00000108010
Uniprot IDs		A0A140VKE1 Q16851	A0A140VJK1 O76003
PDB IDs		3R2W 3R3I 4R7P	2DIY 2WZ9 2YAN 3ZYW
Enriched GO Terms of Interacting Partners?
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