UGDH and AK5

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UGDH	AK5
Description		UDP-glucose 6-dehydrogenase	adenylate kinase 5
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Extracellular Exosome	Cytoplasm Cytosol Centriolar Satellite
	Molecular Function	UDP-glucose 6-dehydrogenase Activity Identical Protein Binding NAD Binding	Adenylate Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding
	Biological Process	Gastrulation With Mouth Forming Second Carbohydrate Metabolic Process Glycosaminoglycan Biosynthetic Process UDP-glucuronate Biosynthetic Process Heparan Sulfate Proteoglycan Biosynthetic Process Chondroitin Sulfate Biosynthetic Process Protein Hexamerization Neuron Development	Nucleoside Diphosphate Phosphorylation ADP Biosynthetic Process DADP Biosynthetic Process Nucleoside Triphosphate Biosynthetic Process Pyrimidine Ribonucleotide Biosynthetic Process ATP Metabolic Process Nucleoside Monophosphate Phosphorylation
Pathways		Formation of the active cofactor, UDP-glucuronate	Interconversion of nucleotide di- and triphosphates
Drugs		NADH Copper
Diseases
GWAS		Haemorrhoidal disease ( 33888516) Response to tofacitinib treatment in psoriasis (herpes zoster) ( 33455090) Response to tofacitinib treatment in psoriasis (herpes zoster)(time to event) ( 33455090)	Body mass index ( 25673413) Chronotype ( 26955885 30696823 27494321) Eosinophil percentage of white cells ( 27863252) Estimated glomerular filtration rate ( 31152163) High light scatter reticulocyte percentage of red cells ( 32888494) Household income (MTAG) ( 31844048) Immature fraction of reticulocytes ( 32888494) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Mean reticulocyte volume ( 32888494) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 26835600 27494321) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes (age of onset) ( 28060188) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		5 interacting genes: AK5 CDC42 ITGB1BP2 RAD51 UGT1A1	7 interacting genes: C7orf26 CPNE6 NUCKS1 RNF114 STRN4 TRIM46 UGDH
Entrez ID		7358	26289
HPRD ID		04535	10472
Ensembl ID		ENSG00000109814	ENSG00000154027
Uniprot IDs		O60701	Q9Y6K8
PDB IDs		2Q3E 2QG4 3ITK 3KHU 3PRJ 3PTZ 3TDK 3TF5 4EDF 4RJT 5TJH 5VR8 5W4X 6C4J 6C4K 6C58 6C5A 6C5Z	2BWJ
Enriched GO Terms of Interacting Partners?
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