UBE2V2 and SHPRH

Number of citations of the paper that reports this interaction (PubMedID 17108083)
103

Data Source:
BioGRID (pull down)

		UBE2V2	SHPRH
Description		ubiquitin conjugating enzyme E2 V2	SNF2 histone linker PHD RING helicase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm UBC13-MMS2 Complex Extracellular Exosome	Nucleosome Nucleoplasm
	Molecular Function	Protein Binding	DNA Binding Helicase Activity Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Hydrolase Activity Ubiquitin Protein Ligase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity ATP-dependent Chromatin Remodeler Activity
	Biological Process	Protein Polyubiquitination DNA Double-strand Break Processing Regulation Of DNA Repair Postreplication Repair Positive Regulation Of Neuron Projection Development Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Error-free Postreplication DNA Repair Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of DNA Repair Positive Regulation Of Synapse Assembly Protein K63-linked Ubiquitination	Protein Polyubiquitination DNA Repair Nucleosome Assembly Cellular Response To DNA Damage Stimulus Protein Ubiquitination
Pathways		Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends Formation of Incision Complex in GG-NER G2/M DNA damage checkpoint E3 ubiquitin ligases ubiquitinate target proteins Antigen processing: Ubiquitination & Proteasome degradation	E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Height ( 31562340)
Interacting Genes		31 interacting genes: BCL10 DZIP3 EGFR HLTF IGSF21 LRIF1 MALT1 MKRN3 MOB4 MUL1 OTUB1 RC3H1 RC3H2 RFFL RNF144A RNF2 RNF8 SHPRH SIAH1 SIAH2 STUB1 SUV39H2 TP53 TRAF2 TRIM5 TRIM54 TRIM63 UBC UBE2N XIAP ZNRF1	12 interacting genes: BORCS6 EDARADD FBXW7 FDFT1 H3C1 H4C1 LPP RAD18 UBE2D1 UBE2N UBE2V2 YWHAG
Entrez ID		7336	257218
HPRD ID		04300	10476
Ensembl ID		ENSG00000169139	ENSG00000146414
Uniprot IDs		A0M8W4 Q15819	B3KX98 Q149N8
PDB IDs		1J74 1J7D 1ZGU 3VON 4NR3 4NRG 4NRI 4ONL 4ONM 4ONN 4ORH 5AIT 7BBD 7BBF	2M85 4QN1
Enriched GO Terms of Interacting Partners?
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