Description |
ubiquitin B |
checkpoint kinase 1 |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- XL844
- Enzastaurin
- CHIR-124
- N-{5-[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]-1H-PYRROLO[2,3-B]PYRIDIN-3-YL}NICOTINAMIDE
- 3-(5-{[4-(AMINOMETHYL)PIPERIDIN-1-YL]METHYL}-1H-INDOL-2-YL)QUINOLIN-2(1H)-ONE
- 2,2'-{[9-(HYDROXYIMINO)-9H-FLUORENE-2,7-DIYL]BIS(OXY)}DIACETIC ACID
- (2S)-1-AMINO-3-[(5-NITROQUINOLIN-8-YL)AMINO]PROPAN-2-OL
- 2-(cyclohexylamino)benzoic acid
- 3-(5-{[4-(AMINOMETHYL)PIPERIDIN-1-YL]METHYL}-1H-INDOL-2-YL)-1H-INDAZOLE-6-CARBONITRILE
- (3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE
- 5-ETHYL-3-METHYL-1,5-DIHYDRO-4H-PYRAZOLO[4,3-C]QUINOLIN-4-ONE
- (5-{3-[5-(PIPERIDIN-1-YLMETHYL)-1H-INDOL-2-YL]-1H-INDAZOL-6-YL}-2H-1,2,3-TRIAZOL-4-YL)METHANOL
- 1-(5-CHLORO-2-METHOXYPHENYL)-3-{6-[2-(DIMETHYLAMINO)-1-METHYLETHOXY]PYRAZIN-2-YL}UREA
- (3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLATE
- 18-CHLORO-11,12,13,14-TETRAHYDRO-1H,10H-8,4-(AZENO)-9,15,1,3,6-BENZODIOXATRIAZACYCLOHEPTADECIN-2-ONE
- 1-(5-CHLORO-2,4-DIMETHOXYPHENYL)-3-(5-CYANOPYRAZIN-2-YL)UREA
- 4-(6-{[(4-METHYLCYCLOHEXYL)AMINO]METHYL}-1,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)BENZOIC ACID
- 4-[3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOL-6-YL]-2-METHOXYPHENOL
- (2R)-1-[(5,6-DIPHENYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO]PROPAN-2-OL
- (2R)-3-{[(4Z)-5,6-DIPHENYL-6,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-YLIDENE]AMINO}PROPANE-1,2-DIOL
- N-(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)GLYCINE
- (5,6-DIPHENYL-FURO[2,3-D]PYRIMIDIN-4-YLAMINO)-ACETIC
- 3-AMINO-3-BENZYL-[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE
- 3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE
- 2-[5,6-BIS-(4-METHOXY-PHENYL)-FURO[2,3-D]PYRIMIDIN-4-YLAMINO]-ETHANOL
- 2-[(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)AMINO]ETHANOL
- REL-(9R,12S)-9,10,11,12-TETRAHYDRO-9,12-EPOXY-1H-DIINDOLO[1,2,3-FG:3',2',1'-KL]PYRROLO[3,4-I][1,6]BENZODIAZOCINE-1,3(2H)-DIONE
- 1-[(2S)-4-(5-phenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl]methanamine
- N-(4-OXO-5,6,7,8-TETRAHYDRO-4H-[1,3]THIAZOLO[5,4-C]AZEPIN-2-YL)ACETAMIDE
- 5,6,7,8-TETRAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE
- [4-amino-2-(tert-butylamino)-1,3-thiazol-5-yl](phenyl)methanone
- 2-(methylsulfanyl)-5-(thiophen-2-ylmethyl)-1H-imidazol-4-ol
- 6-MORPHOLIN-4-YL-9H-PURINE
- 1-[(2S)-4-(5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-4-YL)MORPHOLIN-2-YL]METHANAMINE
- Fostamatinib
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Diseases |
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GWAS |
- Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
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Interacting Genes |
81 interacting genes:
APP
ATXN3
BIRC2
BRAP
BRCA1
CDC25A
CDC34
CDIP1
CDKN1B
CDT1
CDX2
CHEK1
DAZAP2
DESI1
DNMT1
DUSP1
ECT2
EGFR
ELF4
EPS15
ERBB2
FANCD2
FSHR
HDAC6
HGS
HLA-A
IKBKB
IKBKG
JUN
LIG4
LYN
MAPT
MDM2
MTURN
MYBL2
MYC
NR3C1
NTRK1
NTRK2
OPTN
PCNA
PIN1
PLEKHB2
PLSCR4
POLI
PRKN
PSMD4
RABGEF1
RAD23A
RAD23B
RNF11
SDCBP
SH3KBP1
SKP2
SMAD4
SMURF1
SNCA
SNCAIP
SQSTM1
STUB1
SYK
TAX1BP1
TGFBR1
TP53
TRAF6
TRIM37
TRIM5
UBAC1
UBASH3A
UBASH3B
UBE2D2
UBE2K
UBE2N
UBE2S
UBQLN1
UBQLN2
UIMC1
USP1
USP30
WWOX
XIAP
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54 interacting genes:
AATF
AKT1
APP
ATM
ATR
ATXN3
BCL2L1
BLM
BRCA1
BRCA2
CDC25A
CDC25B
CDC25C
CHUK
CLSPN
CNTN2
CSNK2B
CUL1
CUL4A
DTL
FANCE
HSP90AA1
ILKAP
LATS2
MAPT
MCM6
MCM7
MCPH1
MDM4
NFRKB
PDE2A
PIGM
PRKAA1
PRKDC
RAD23A
RAD51
RB1
RELA
SMAD4
TIMELESS
TLK1
TOPBP1
TP53
TP53BP1
TRAF4
UBA1
UBA2
UBB
UBE2T
USP3
XIAP
XPO1
XRCC6
YWHAG
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Entrez ID |
7314 |
1111 |
HPRD ID |
06771 |
04356 |
Ensembl ID |
ENSG00000170315
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ENSG00000149554
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Uniprot IDs |
P0CG47
Q5U5U6
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B4DT73
E7EPP6
O14757
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PDB IDs |
2KHW
2MBB
2MRO
2MSG
2N13
4UEL
4UF6
4WHV
4WLR
4WUR
4XOF
4ZFR
4ZFT
4ZPZ
4ZUX
5BNB
5CAW
5CRA
5CVM
5CVN
5CVO
5D0K
5D0M
5DFL
5DK8
5E6J
5EDV
5EMZ
5EYA
5GJQ
5GO7
5GO8
5GOB
5GOC
5GOD
5GOG
5GOH
5GOI
5GOJ
5GOK
5H7S
5IBK
5IFR
5JBY
5JG6
5JP3
5JTJ
5JTV
5K9P
5KGF
5KHY
5KYC
5KYD
5KYE
5KYF
5L8H
5L8W
5L9T
5LN1
5LRV
5LRW
5LRX
5M93
5MNJ
5N2W
5N38
5NL5
5NLJ
5NVG
5O44
5O6T
5OHK
5OHL
5OHN
5OHP
5TOF
5TOG
5TUT
5TXK
5UJL
5UJN
5ULF
5ULH
5ULK
5V1Y
5V1Z
5VEY
5VF0
5VNZ
5VO0
5VZM
5VZW
5W46
5WFI
5X3M
5X3N
5X3O
5XBO
5XDP
5XK4
5XK5
5XPK
5YDR
5YIJ
5YIK
5YMY
5YT6
5ZBU
5ZD0
6ASR
6BVA
6BYH
6C16
6CP2
6DGF
6EI1
6FDK
6FGE
6FTX
6FX4
6FYH
6GLC
6GZS
6H4H
6HEI
6HEK
6IF1
6ISU
6JB6
6JB7
6JMA
6K4I
6K9P
6KOW
6KOX
6LP2
6MSB
6MSD
6MSE
6MSG
6N13
6NJG
6O96
6OAM
6PGV
6PZV
6QF8
6QK9
6QML
6TBM
6UH5
6XAA
7CAP
7JMS
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1IA8
1NVQ
1NVR
1NVS
1ZLT
1ZYS
2AYP
2BR1
2BRB
2BRG
2BRH
2BRM
2BRN
2BRO
2C3J
2C3K
2C3L
2CGU
2CGV
2CGW
2CGX
2E9N
2E9O
2E9P
2E9U
2E9V
2GDO
2GHG
2HOG
2HXL
2HXQ
2HY0
2QHM
2QHN
2R0U
2WMQ
2WMR
2WMS
2WMT
2WMU
2WMV
2WMW
2WMX
2X8D
2X8E
2X8I
2XEY
2XEZ
2XF0
2YDI
2YDJ
2YDK
2YER
2YEX
2YM3
2YM4
2YM5
2YM6
2YM7
2YM8
2YWP
3F9N
3JVR
3JVS
3NLB
3OT3
3OT8
3PA3
3PA4
3PA5
3TKH
3TKI
3U9N
4FSM
4FSN
4FSQ
4FSR
4FST
4FSU
4FSW
4FSY
4FSZ
4FT0
4FT3
4FT5
4FT7
4FT9
4FTA
4FTC
4FTI
4FTJ
4FTK
4FTL
4FTM
4FTN
4FTO
4FTQ
4FTR
4FTT
4FTU
4GH2
4HYH
4HYI
4JIK
4QYE
4QYF
4QYG
4QYH
4RVK
4RVL
4RVM
5DLS
5F4N
5OOP
5OOR
5OOT
5OP2
5OP4
5OP5
5OP7
5OPB
5OPR
5OPS
5OPU
5OPV
5OQ5
5OQ6
5OQ7
5OQ8
5WI2
6FC8
6FCF
6FCK
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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