TYMS and EPB41L3

		TYMS	EPB41L3
Description		thymidylate synthetase	erythrocyte membrane protein band 4.1 like 3
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytosol	Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Cell Junction Axolemma Paranode Region Of Axon Juxtaparanode Region Of Axon
	Molecular Function	Translation Repressor Activity, MRNA Regulatory Element Binding Thymidylate Synthase Activity Folic Acid Binding Protein Homodimerization Activity Sequence-specific MRNA Binding	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein-membrane Anchor Activity
	Biological Process	DTMP Biosynthetic Process DTTP Biosynthetic Process Aging Circadian Rhythm Response To Xenobiotic Stimulus Response To Toxic Substance Negative Regulation Of Translation Uracil Metabolic Process Methylation Response To Progesterone Response To Vitamin A Response To Cytokine Tetrahydrofolate Interconversion Response To Ethanol Response To Organophosphorus Developmental Growth Cartilage Development Response To Glucocorticoid Response To Folic Acid Intestinal Epithelial Cell Maturation DNA Biosynthetic Process Liver Regeneration	Regulation Of Cell Growth Protein Localization To Paranode Region Of Axon Apoptotic Process Biological_process Regulation Of Cell Shape Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Paranodal Junction Assembly Actomyosin Structure Organization Myelin Maintenance Neuron Projection Morphogenesis Protein Localization To Juxtaparanode Region Of Axon Protein Localization To Plasma Membrane
Pathways		Interconversion of nucleotide di- and triphosphates G1/S-Specific Transcription	Neurexins and neuroligins Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs		Raltitrexed Floxuridine Trifluridine Gemcitabine Fluorouracil Methotrexate Pemetrexed Capecitabine Thymidine monophosphate 10-Propargyl-5,8-Dideazafolic Acid Deoxyuridine monophosphate S,S-(2-Hydroxyethyl)Thiocysteine Thymectacin ANX-510 OSI-7904L Pralatrexate 2,4-Diamino-5-phenyl-6-ethylpyrimidine N-[2-Chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE Tegafur Tegafur-uracil
Diseases
GWAS		Leukocyte telomere length ( 32109421 31171785) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Testicular germ cell tumor ( 28604728) Urinary metabolite levels in chronic kidney disease ( 31959995)	Cerebral amyloid deposition (PET imaging) ( 26252872) Chronic kidney disease ( 31152163) Diverticular disease ( 30177863) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Glomerular filtration rate (creatinine) ( 28452372) Lacunar stroke ( 33773637) Optic nerve head parameters (multi-trait analysis) ( 31798171) Sleep duration ( 25469926) Social communication problems ( 24564958) Thyroid nodules ( 30099483) Vertical cup-disc ratio ( 31798171)
Interacting Genes		12 interacting genes: CDC42 EPB41L3 ITGAM NAPG NDUFV2 OCRL SH3GL2 SMCHD1 TAF3 THOC1 UPF2 YES1	20 interacting genes: ATXN1L CADM1 CEP152 CLNS1A CNTNAP2 HSPB1 IGSF21 MBIP PAXIP1 PSEN1 SPANXN2 SPTBN1 TCF4 TYMS UNC13A YWHAB YWHAG YWHAH YWHAQ YWHAZ
Entrez ID		7298	23136
HPRD ID		01774	05622
Ensembl ID		ENSG00000176890	ENSG00000082397
Uniprot IDs		P04818 Q53Y97	A0A0A0MRA8 A8K968 Q9Y2J2
PDB IDs		1HVY 1HW3 1HW4 1HZW 1I00 1JU6 1JUJ 1YPV 2ONB 2RD8 2RDA 3EAW 3EBU 3ED7 3EDW 3EF9 3EGY 3EHI 3EJL 3GG5 3GH0 3GH2 3H9K 3HB8 3N5E 3N5G 3OB7 4E28 4FGT 4G2O 4G6W 4GD7 4GYH 4H1I 4JEF 4KPW 4O1U 4O1X 4UP1 5HS3 5WRN 5X4W 5X4X 5X4Y 5X5A 5X5D 5X5Q 5X66 5X67 5X69 6OJU 6OJV 6PF3 6PF4 6PF5 6PF6 6QXG 6QXH 6QYQ 6R2E	2HE7 3BIN 5RYM 5RYN 5RYO 5RYP 5RYQ 5RYR 5RYS 5RYT 5RYU 5RYV 5RYW 5RYX 5RYY 5RYZ 5RZ0 5RZ1 5RZ2 5RZ3 5RZ4 5RZ5 5RZ6 5RZ7 5RZ8 5RZ9 5RZA 5RZB 5RZC 5RZD 5RZE 5RZF 5RZG 5RZH 5RZI 5RZJ 5RZK 5RZL 5RZM 5RZN 5RZO 5RZP 5RZQ 5RZR 5RZS 5RZT 5RZU 5RZV 5RZW 5RZX 5RZY 5RZZ 5S00 6IBE
Enriched GO Terms of Interacting Partners?
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