TTPA and SLC35E3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TTPA	SLC35E3
Description		alpha tocopherol transfer protein	solute carrier family 35 member E3
Image			No pdb structure
GO Annotations	Cellular Component	Late Endosome Cytosol	Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Vitamin E Binding Phosphatidylinositol-3,4-bisphosphate Binding Lipid Transfer Activity Phosphatidylinositol Bisphosphate Binding	Nucleotide-sugar Transmembrane Transporter Activity Protein Binding Antiporter Activity
	Biological Process	Lipid Metabolic Process Response To Nutrient Response To PH Developmental Process Vitamin E Metabolic Process Vitamin Transport Intracellular PH Reduction Negative Regulation Of Cell Death Intermembrane Lipid Transfer	Nucleobase-containing Compound Transport Transmembrane Transport Carbohydrate Derivative Transport
Pathways		Vitamin E
Drugs
Diseases
GWAS		Response to esketamine (responder status) in treatment resistant depression ( 32724131) Response to esketamine in treatment resistant depression ( 32724131)	Mean reticulocyte volume ( 32888494) White blood cell count ( 20139978)
Interacting Genes		47 interacting genes: AGTRAP APOA5 APOC2 APP ARFIP2 ARMC12 BIRC7 CISD2 CMTM4 CMTM5 COQ3 CYSRT1 DGAT2L6 DHODH FADS6 FAM114A2 FAM25A FAM25C FAM25G FGF14 FKBP7 GOLGA2 HSD17B11 JOSD2 KRTAP10-7 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 LEUTX MAL2 MMS22L MRM1 NBPF19 NDUFA7 NOTCH2NLA PEX12 REEP2 RPRM SAR1A SCAMP1 SCAMP5 SDR16C5 SLC35E3 SYNGR3 THAP4 TPD52	23 interacting genes: ADIPOQ ATP6V0C BCL2L2 BIK BNIP2 C4orf3 CSGALNACT2 FAM209A FFAR2 FXYD6 GET1 GPR25 LNPEP PLP1 RUSF1 SELENOK SLC66A2 SPG21 SSMEM1 TMEM14B TMEM234 TMEM60 TTPA
Entrez ID		7274	55508
HPRD ID		02685	15375
Ensembl ID		ENSG00000137561	ENSG00000175782
Uniprot IDs		P49638	A0A024RB82 Q7Z769
PDB IDs		1OIP 1OIZ 1R5L 5MUE 5MUG 6ZPD
Enriched GO Terms of Interacting Partners?
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