TSNAX and KCNE4

Number of citations of the paper that reports this interaction (PubMedID 20498229)
13

Data Source:
BioGRID (two hybrid)

		TSNAX	KCNE4
Description		translin associated factor X	potassium voltage-gated channel subfamily E regulatory subunit 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm	Integral Component Of Membrane Apical Plasma Membrane
	Molecular Function	DNA Binding Single-stranded DNA Binding RNA Binding Endoribonuclease Activity A2A Adenosine Receptor Binding Sequence-specific DNA Binding Protein-containing Complex Binding Metal Ion Binding	Delayed Rectifier Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Transmembrane Transporter Binding Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
	Biological Process	Spermatogenesis Cell Differentiation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Regulation Of Heart Rate By Cardiac Conduction Potassium Ion Export Across Plasma Membrane Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Delayed Rectifier Potassium Channel Activity
Pathways		Small interfering RNA (siRNA) biogenesis	Phase 3 - rapid repolarisation Phase 2 - plateau phase
Drugs			Enflurane Promethazine Miconazole
Diseases
GWAS		Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451) Metabolite levels ( 23823483)	Acute lymphoblastic leukemia (childhood) ( 19684603) Body mass index ( 20966902) Coronary artery disease in type 1 diabetes ( 32077919) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Fasting plasma glucose ( 32902719) Logical memory (delayed recall) in normal cognition ( 29274321) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean platelet volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494) Platelet distribution width ( 32888494) Recurrent major depressive disorder x sex interaction ( 34099189) Reticulocyte count ( 32888494) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Waist circumference ( 20966902) Weight ( 28552196)
Interacting Genes		41 interacting genes: AIMP1 AKAP9 BEX3 BLOC1S5 C1D CARD9 CDK5RAP2 CEP68 CKAP4 COG6 EMILIN1 GADD45G GOLGA3 GPATCH2 GRIPAP1 HMGB2 KCNE4 KLC3 KRT31 LDB2 LDOC1 LZTS2 MRFAP1L1 NSMCE2 NTAQ1 PBXIP1 PMF1 PRPF18 RALYL RFC5 SOGA1 SPRED2 SUN1 SYCE2 SYT17 TCF12 TCP11L1 TSN TSNAXIP1 UBE2I VPS28	10 interacting genes: CAMLG FLNA GET3 KCNA1 KCNQ1 OBSL1 PRKCA TCF7L2 TRDN TSNAX
Entrez ID		7257	23704
HPRD ID		04270	09689
Ensembl ID		ENSG00000116918
Uniprot IDs		A0A024R3V8 Q99598	A5H1P5 Q8WWG9
PDB IDs		3PJA 3QB5
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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