TRIP6 and TBC1D22B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRIP6	TBC1D22B
Description		thyroid hormone receptor interactor 6	TBC1 domain family member 22B
Image
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion
	Molecular Function	RNA Binding Interleukin-1 Receptor Binding Protein Binding Kinase Binding Metal Ion Binding Thyroid Hormone Receptor Binding	GTPase Activator Activity Protein Binding 14-3-3 Protein Binding
	Biological Process	Signal Transduction Positive Regulation Of Cell Migration Chordate Embryonic Development Focal Adhesion Assembly Positive Regulation Of NIK/NF-kappaB Signaling	Intracellular Protein Transport Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Nonunion in individuals with fractures ( 30680360) Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020) Serum alkaline phosphatase levels ( 33547301)	Acne (severe) ( 24927181) Blood glucose levels ( 31928498) Platelet count ( 27863252) Systolic blood pressure ( 31928498) Triglyceride levels ( 31928498)
Interacting Genes		165 interacting genes: ABI2 ADAMTSL4 AQP1 ARNT2 ATN1 ATP23 ATP5PO ATXN1 AXIN1 BAG3 BCAR1 BEX2 BYSL C11orf87 CATSPER1 CBLC CCDC120 CCDC187 CCDC24 CCL5 CEP57L1 CNTF CREB5 CRYBA4 CTAG2 DHX37 DMRT3 DTX2 EFHC1 EPDR1 ERBB2 EXOC3-AS1 FAM124B FAM222B FARS2 FAS FASLG FHL3 FOXD4L1 FRS3 GAD1 GATA1 GDPD5 GFI1B GLIS3 GNAI2 GNE GPS2 GSE1 HCK HLA-DPB1 HOXA1 HOXA9 HOXB9 HOXC8 HYKK IL16 ILF3 INCA1 IP6K3 IQCN ITGB4 KCTD9 KIF1A KIR2DL4 KLK15 KPRP KRTAP26-1 LMO2 LNX1 LPAR2 MAPKBP1 MEMO1 METTL17 MIEN1 MIIP MISP MSRB3 MVP NCK2 NEDD9 NEU4 NOL4L-DT NR1D2 NSMF NUP210 ODF1 OIP5 OTUB2 OTX1 PATZ1 PDGFRB PDLIM4 PER1 PIGS PIN1 PLEKHN1 POM121 POM121L4P PPP1R16A PRKAA1 PRKAA2 PTK2 PTPN13 PTPN14 PXN RAD23A RANBP3L RELN RERE RFX3 RHOA RHOQ RNF213 RNF214 SAXO1 SCAND1 SCRIB SETDB1 SHISA6 SIK3 SLC15A3 SLC25A6 SMAD1 SMG9 SNAI1 SON SRC STAC STK16 SVIL SYNGAP1 TAB1 TBC1D22B TCAF1 TEKT4 TENT5C THRB TIE1 TLE5 TLR2 TMSB4X TPM3 TPM4 TRAF3IP2 TRAPPC2L TRIM29 TSGA10IP TSSK3 TTC23 TTLL10 TXN2 TXNDC5 USP2 VASN VCL WT1-AS YPEL3 ZBP1 ZIC1 ZNF541 ZNF580 ZNF581 ZNF688 ZNF785	58 interacting genes: AP1B1 ARHGEF9 BLZF1 CALCOCO2 CARD10 CCDC57 CCDC88B CDR2 CEP63 CEP70 COG6 DAPK1 DDIT4L DEUP1 EFHC2 EXOC8 FHL3 FXR1 FXR2 GFAP GOLGA2 HMG20A HOMER3 HOOK2 HSD17B14 IKZF3 KIFC3 KRT34 KRT40 LHX8 LIMS1 LRRK2 MFHAS1 MID2 MTUS2 PICK1 PLEKHG4 PNMA5 RBM10 RBM48 REL SIAH1 SLAIN1 SORBS3 SPATA2 TACC3 TEPSIN TEX11 TP53BP2 TRIM23 TRIM27 TRIM54 TRIP6 VPS52 ZFP90 ZNF438 ZNF76 ZSCAN4
Entrez ID		7205	55633
HPRD ID		04242	15475
Ensembl ID		ENSG00000087077	ENSG00000065491
Uniprot IDs		Q15654	Q9NU19
PDB IDs		1X61 2DLO	6D0S
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?