HSP90B1 and CAMLG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HSP90B1	CAMLG
Description		heat shock protein 90 beta family member 1	calcium modulating ligand
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Focal Adhesion Membrane Midbody Protein-containing Complex Sarcoplasmic Reticulum Lumen Endoplasmic Reticulum Chaperone Complex Melanosome Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome Endocytic Vesicle Lumen	Cytoplasm Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane GET Complex
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding ATP Binding Protein Phosphatase Binding Low-density Lipoprotein Particle Receptor Binding Unfolded Protein Binding	Protein Binding Ubiquitin Protein Ligase Binding Cell Adhesion Molecule Binding
	Biological Process	Response To Hypoxia Protein Folding Protein Transport Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Actin Rod Assembly Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity Sequestering Of Calcium Ion Cellular Response To ATP	B Cell Homeostasis Defense Response Signal Transduction Vesicle-mediated Transport Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Trafficking and processing of endosomal TLR Scavenging by Class A Receptors Scavenging by Class A Receptors ATF6 (ATF6-alpha) activates chaperone genes Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Interleukin-4 and Interleukin-13 signaling Post-translational protein phosphorylation	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		Rifabutin 2-Chlorodideoxyadenosine Geldanamycin Diglyme N-Ethyl-5'-Carboxamido Adenosine Radicicol METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATE 2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATE Copper	Cyclosporine
Diseases
GWAS		Blood protein levels ( 29875488) Metabolite levels ( 23823483) Soluble VCAM-1 levels ( 31217265)	Height ( 18391951)
Interacting Genes		39 interacting genes: APOB ASGR1 BIRC2 CACYBP CAMLG CCT2 CSNK2A1 CSNK2A2 CYSLTR2 EGFR EPB41L4B ERBB2 ESR1 FANCC GPR37 HSPA9 LINC01554 LRP1 MAPK6 MDM2 MMP17 MTTP NKX3-1 OGT OS9 POLR2E PTEN PTPN11 RXFP3 SGTB SIRPA SUPT6H TG TLR1 TLR2 TLR4 TP53 TXNDC11 UBASH3A	22 interacting genes: ADIPOQ AGR2 EGFR ETNK1 F11R GET1 GET3 HSP90B1 KCNA2 KCNE4 LAT LCN2 OCIAD1 PBXIP1 PGRMC1 PKHD1 PPIB STT3B TMEM31 TNFRSF13B TXNDC12 VWC2
Entrez ID		7184	819
HPRD ID		01860	03073
Ensembl ID		ENSG00000166598	ENSG00000164615
Uniprot IDs		P14625 V9HWP2	P49069
PDB IDs		4NH9	6SO5
Enriched GO Terms of Interacting Partners?
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