NR2C2 and NR2C1

Number of citations of the paper that reports this interaction (PubMedID 12093744)
57

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo, in vitro)

		NR2C2	NR2C1
Description		nuclear receptor subfamily 2 group C member 2	nuclear receptor subfamily 2 group C member 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm	Chromatin Nucleoplasm PML Body
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Signaling Receptor Activity Protein Homodimerization Activity Histone Deacetylase Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Spermatogenesis Nervous System Development Cell Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Embryonic Development Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cell Differentiation Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Anatomical Structure Development
Pathways		Nuclear Receptor transcription pathway	Nuclear Receptor transcription pathway SUMOylation of intracellular receptors
Drugs
Diseases
GWAS		Alcohol and nicotine co-dependence ( 22488850)	Body fat mass ( 28552196) Chromosomal aberration frequency (chromosome type) ( 31586183) Coronary artery disease ( 32469254) Intracranial aneurysm ( 33199917) Trunk fat mass ( 28552196)
Interacting Genes		24 interacting genes: AR CD2AP CDC37 CHUK ESR1 FKBP5 HDAC4 HNF4A HSP90AA1 HSP90AB1 IKBKB ITSN2 JAZF1 KDM1A NR2C1 NR2C2AP PEBP1 RAC1 RPL36 RXRB TAB1 TAB2 TRAF2 TRIM55	9 interacting genes: AR ESR1 HDAC3 HDAC4 NR2C2 NRIP1 NUDT3 RARA SYNE2
Entrez ID		7182	7181
HPRD ID		03253	03318
Ensembl ID		ENSG00000177463	ENSG00000120798
Uniprot IDs		F2YGU2 P49116	H9NIM2 H9NIM3 P13056
PDB IDs		3P0U
Enriched GO Terms of Interacting Partners?
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