TPT1 and STEAP3

Number of citations of the paper that reports this interaction (PubMedID 15319436)
62

Data Source:
HPRD (in vitro, two hybrid)

		TPT1	STEAP3
Description		tumor protein, translationally-controlled 1	STEAP3 metalloreductase
Image
GO Annotations	Cellular Component	Spindle Pole Extracellular Space Nucleus Nucleoplasm Cytoplasm Multivesicular Body Cytosol Cytoplasmic Microtubule Extracellular Exosome	Cytoplasm Endosome Multivesicular Body Plasma Membrane Endosome Membrane Integral Component Of Membrane
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding	Protein Binding Cupric Reductase Activity Oxidoreductase Activity, Acting On Metal Ions, NAD Or NADP As Acceptor Metal Ion Binding Ferric-chelate Reductase (NADPH) Activity
	Biological Process	Calcium Ion Transport Cellular Calcium Ion Homeostasis Response To Virus Stem Cell Population Maintenance Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Ectoderm Development	Apoptotic Process Cell Cycle Protein Secretion Copper Ion Import Transferrin Transport Iron Ion Homeostasis
Pathways			TP53 Regulates Transcription of Genes Involved in Cytochrome C Release CDC42 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOF GTPase cycle Transferrin endocytosis and recycling
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Type 2 diabetes ( 25760438)	Cocaine dependence ( 23958962) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Renal cell carcinoma x sex interaction ( 31231134)
Interacting Genes		30 interacting genes: APP ATP1A1 ATP1A2 BCL2L1 CALM1 DBN1 EEF1A1 EEF1A2 EEF1B2 EEF1D FANCA HSPB1 IKBKG LIG4 MCL1 MCPH1 MDM2 MLC1 NKX3-1 NOTCH3 PER2 PLK1 RBBP6 RPLP1 SNX6 SPP1 STEAP3 TRIP13 TUBB2A VHL	6 interacting genes: BAD BNIP3L MTDH PKMYT1 SETD7 TPT1
Entrez ID		7178	55240
HPRD ID		15979	10285
Ensembl ID		ENSG00000133112	ENSG00000115107
Uniprot IDs		A0A024RDY2 A0A0B4J2C3 A0A0P1J1R0 P13693	A1P3F0 B8ZZX6 Q658P3
PDB IDs		1YZ1 2HR9 3EBM 4Z9V 5O9L 5O9M 6IZB 6IZE	2VNS 2VQ3
Enriched GO Terms of Interacting Partners?
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