C2 and SEC11C

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

C2

SEC11C

Description complement C2 SEC11 homolog C, signal peptidase complex subunit
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Advanced age-related macular degeneration ( 26691988)
  • Age at first sexual intercourse ( 34211149)
  • Age-related macular degeneration ( 20385819 20385826 23455636 21665990)
  • Age-related macular degeneration (choroidal neovascularisation) ( 22705344)
  • Age-related macular degeneration (geographic atrophy) ( 22705344)
  • Asthma ( 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Blood protein levels ( 29875488 28240269)
  • Body shape index ( 34021172)
  • Circulating myeloperoxidase levels (serum) ( 23620142)
  • Clostridioides difficle infection ( 33841421)
  • Coffee consumption ( 31046077)
  • Coronary artery disease ( 29212778 30104761)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Disease progression in age-related macular degeneration ( 29346644)
  • Early age-related macular degeneration ( 32843070)
  • Endometriosis ( 28881265)
  • Estimated glomerular filtration rate ( 31451708)
  • Estimated glomerular filtration rate in diabetes ( 31451708)
  • Hepatocellular carcinoma ( 21105107)
  • Hip circumference adjusted for BMI ( 34021172)
  • Inflammatory bowel disease ( 28067908)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Mosquito bite size ( 28199695)
  • Platelet aggregation ( 29185836)
  • Prostate cancer ( 23535732)
  • Sulfasalazine-induced agranulocytosis ( 28762467)
  • Systemic lupus erythematosus ( 24871463)
  • Ulcerative colitis ( 28067908)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • Youthful appearance (self-reported) ( 32339537)
Interacting Genes 15 interacting genes: C3 C4B C5 CREB3 EBP ERGIC3 FAM209A MASP1 MUC1 PSMA4 SEC11C SLC10A1 SLC35C2 STOM TNF 23 interacting genes: BTN2A2 C2 CADM3 GLP1R HMOX1 MFF PLPP6 PRSS23 RTP2 SCD SELENOM SERP1 STX12 TMEM128 TMEM243 TMEM254 TMEM42 TREX1 TSNARE1 UBE2J1 VAMP1 VAMP4 VAPA
Entrez ID 717 90701
HPRD ID 08939 15310
Ensembl ID ENSG00000166278 ENSG00000166562
Uniprot IDs A0A0G2JL69 B4DQI1 B4DV48 P06681 Q53HP3 Q5JP69 Q8N6L6 K7EJQ7 Q9BY50
PDB IDs 2I6Q 2I6S 2ODP 2ODQ 3ERB
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?