C1QC and RALA

		C1QC	RALA
Description		complement C1q C chain	RAS like proto-oncogene A
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GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Synapse Collagen-containing Extracellular Matrix Blood Microparticle Postsynapse	Mitochondrion Plasma Membrane Focal Adhesion Cell Surface Endocytic Vesicle Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Exosome Flemming Body
	Molecular Function	Protein Binding	GTPase Activity G Protein Activity Protein Binding GTP Binding Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding
	Biological Process	Immune Response Complement Activation, Classical Pathway Negative Regulation Of Granulocyte Differentiation Innate Immune Response Negative Regulation Of Macrophage Differentiation Synapse Pruning	Neural Tube Closure Exocytosis Chemotaxis Cell Cycle Signal Transduction Ras Protein Signal Transduction Regulation Of Exocytosis Actin Cytoskeleton Reorganization Cell Division Positive Regulation Of Filopodium Assembly Membrane Raft Localization Establishment Of Protein Localization To Mitochondrion Positive Regulation Of Mitochondrial Fission
Pathways		Initial triggering of complement Classical antibody-mediated complement activation Regulation of Complement cascade	Translocation of SLC2A4 (GLUT4) to the plasma membrane p38MAPK events Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		Cetuximab Etanercept Palivizumab Daclizumab Bevacizumab Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Guanosine-5'-Diphosphate
Diseases
GWAS		Blood protein levels ( 30072576 29875488)
Interacting Genes		7 interacting genes: C1QA C1QB FKBP2 PTX3 RALA UBQLN2 ZNF534	36 interacting genes: ACTB AKAP10 ARF1 C1QC CALM1 CNKSR2 CTCF EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA GCK GLS2 HOXA2 HSPB1 INHBA LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RASSF5 REPS1 RGL2 RGL4 SMAD4 YBX3
Entrez ID		714	5898
HPRD ID		00395	01549
Ensembl ID		ENSG00000159189	ENSG00000006451
Uniprot IDs		A0A024RAA7 P02747	P11233
PDB IDs		1PK6 2JG8 2JG9 2WNU 2WNV 5HKJ 5HZF 6FCZ 6Z6V	1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV 6P0I 6P0J 6P0K 6P0L 6P0M 6P0N 6P0O
Enriched GO Terms of Interacting Partners?
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