TNFAIP1 and HEXIM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TNFAIP1	HEXIM2
Description		TNF alpha induced protein 1	HEXIM P-TEFb complex subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Cytosol Cul3-RING Ubiquitin Ligase Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Cyclin Binding Small GTPase Binding Identical Protein Binding	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding SnRNA Binding Identical Protein Binding 7SK SnRNA Binding
	Biological Process	Apoptotic Process Immune Response Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Protein Homooligomerization	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated
Pathways		RND3 GTPase cycle RND2 GTPase cycle
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Low density lipoprotein cholesterol levels ( 29403010) Osteoprotegerin levels ( 25080503)	Asthma ( 31959851 31619474) Brain morphology (MOSTest) ( 32665545) Craniofacial microsomia ( 26853712) Male-pattern baldness ( 28196072) Systolic blood pressure ( 19430483)
Interacting Genes		34 interacting genes: ARMC7 ARNT CAPN7 CARD9 CDC37 CSNK2B DAPP1 EPHA2 EPM2AIP1 EXOSC5 FXR1 FXR2 HAT1 HEXIM2 KCTD10 KCTD13 KDM1A LNX1 NTAQ1 NXF1 POLR1C PRKAG1 PSMA1 RHOA RHOB RIN3 SMARCA2 SMARCB1 STK16 SUV39H1 SVIL TRIM54 ZDHHC17 ZMYND19	49 interacting genes: ADAMTSL4 AHCYL1 AP2M1 CACNB2 CCDC33 CCNT1 CDK9 CFP CTIF DBF4B EGFL7 FAM161A GAS8 GATA1 HEXIM1 HOXA1 HSF2BP IHO1 KPNA3 KPRP KRTAP13-3 LNX1 MEOX2 PICK1 PIM1 PIN1 PRDM14 PSMA1 RNPS1 SAXO1 SDCBP SPRED1 SPRY1 SPRY2 TADA3 TCF12 TERF1 TERF2 TLE5 TNFAIP1 TRIM14 YPEL3 ZNF250 ZNF426 ZNF500 ZNF558 ZNF655 ZNF699 ZNF789
Entrez ID		7126	124790
HPRD ID		01856	08129
Ensembl ID		ENSG00000109079	ENSG00000168517
Uniprot IDs		Q13829	Q96MH2
PDB IDs
Enriched GO Terms of Interacting Partners?
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