GPR137B and NLGN4X

		GPR137B	NLGN4X
Description		G protein-coupled receptor 137B	neuroligin 4 X-linked
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Integral Component Of Plasma Membrane Membrane	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Integral Component Of Membrane Dendrite Synapse Excitatory Synapse Spanning Component Of Membrane Presynapse Postsynaptic Density Membrane Symmetric, GABA-ergic, Inhibitory Synapse Asymmetric, Glutamatergic, Excitatory Synapse Integral Component Of Postsynaptic Specialization Membrane
	Molecular Function	Protein Binding	Protein Binding Chloride Ion Binding Signaling Receptor Activity Neurexin Family Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding Scaffold Protein Binding
	Biological Process	Autophagy Regulation Of Autophagy Regulation Of Macrophage Activation Regulation Of GTPase Activity Negative Regulation Of Osteoclast Differentiation Negative Regulation Of Bone Resorption Positive Regulation Of Protein Localization To Lysosome Positive Regulation Of TORC1 Signaling	Brainstem Development Neuron Cell-cell Adhesion Chemical Synaptic Transmission Learning Cerebellum Development Neuron Differentiation Adult Behavior Social Behavior Organ Growth Cell-cell Junction Organization Synaptic Vesicle Endocytosis Modulation Of Chemical Synaptic Transmission Synapse Organization Vocalization Behavior Negative Regulation Of Excitatory Postsynaptic Potential Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Presynapse Assembly
Pathways			Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Metabolite levels ( 23823483) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309) Systolic blood pressure ( 27841878) Waist circumference adjusted for body mass index ( 28552196)	Metabolite levels ( 23823483) Schizophrenia ( 25056061 29483656)
Interacting Genes		4 interacting genes: AFF3 APP NLGN4X TRIM32	7 interacting genes: CCL22 DLG4 DLGAP2 FES GPR137B LCP1 ZSCAN31
Entrez ID		7107	57502
HPRD ID		06878	02336
Ensembl ID		ENSG00000077585	ENSG00000146938
Uniprot IDs		O60478	A0A024RBV0 A8K4S1 B3KP11 Q8N0W4
PDB IDs			2WQZ 2XB6 3BE8
Enriched GO Terms of Interacting Partners?
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