BUB1 and PPP3R2

Number of citations of the paper that reports this interaction (PubMedID 24412244)
2

Data Source:
BioGRID (two hybrid)

		BUB1	PPP3R2
Description		BUB1 mitotic checkpoint serine/threonine kinase	protein phosphatase 3 regulatory subunit B, beta
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleoplasm Cytosol Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Calcium Ion Binding Protein Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity
	Biological Process	Protein Phosphorylation Apoptotic Process Regulation Of Sister Chromatid Cohesion Mitotic Cell Cycle Checkpoint Signaling Mitotic Spindle Assembly Checkpoint Signaling Cell Population Proliferation Cell Division Meiotic Sister Chromatid Cohesion, Centromeric Regulation Of Chromosome Segregation	Regulation Of Catalytic Activity
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs			Cyclosporine Voclosporin
Diseases
GWAS
Interacting Genes		63 interacting genes: AKT1 ALDOB ANP32B AOPEP AP1B1 AP2B1 AP3B1 AP4B1 APC ARIH2 BAAT BUB3 CCDC180 CDC14B CDC20 CDK1 CDK8 CORO2A CRK CTSV CYLC2 DVL1 EIF4EBP1 FANCC FBP1 FBP2 FBXO7 FRAT2 GALNT12 HDAC1 HEMGN HRAS HSD17B3 IGFBP3 KNL1 LEF1 MAP2K1 MAPK3 MSANTD3 NANS PLK1 PPP2CB PPP3R2 RAE1 RASA1 RDH12 SEC61B SFRP2 SFRP4 SHC1 SMAD1 STX17 SVIL TBC1D2 TDRD7 TGFB1 TMEFF1 TMOD1 TRMO TSTD2 XPA ZNF189 ZNF510	20 interacting genes: APC AURKA BUB1 CCND1 CD14 DLC1 DYNLL1 ERP44 FBXW7 KRT34 MLH3 MSH2 PDGFRL PPP3CA PTPN12 PTPRJ RAB32 SMAD4 TBC1D10C TFCP2
Entrez ID		699	5535
HPRD ID		03907	10164
Ensembl ID		ENSG00000169679	ENSG00000188386
Uniprot IDs		B4DYG2 O43683	Q96LZ3
PDB IDs		2LAH 4A1G 4QPM 4R8Q 5DMZ 6F7B
Enriched GO Terms of Interacting Partners?
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