ELOB and USP33

Number of citations of the paper that reports this interaction (PubMedID 19706539)
39

Data Source:
BioGRID (affinity chromatography technology)

		ELOB	USP33
Description		elongin B	ubiquitin specific peptidase 33
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GO Annotations	Cellular Component	Nucleoplasm Cytosol VCB Complex Cul2-RING Ubiquitin Ligase Complex Cul5-RING Ubiquitin Ligase Complex Elongin Complex	Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol Focal Adhesion VCB Complex Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	G Protein-coupled Receptor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding Zinc Ion Binding Small GTPase Binding Ubiquitin Binding
	Biological Process	Transcription Elongation From RNA Polymerase II Promoter Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein-containing Complex Assembly	Ubiquitin-dependent Protein Catabolic Process Endocytosis Axon Guidance Regulation Of G Protein-coupled Receptor Signaling Pathway Cellular Response To Starvation Regulation Of Autophagy Cell Migration Protein Deubiquitination Negative Regulation Of Protein Binding Positive Regulation Of Protein Binding Protein Stabilization Centrosome Duplication Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination
Pathways		Formation of RNA Pol II elongation complex Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation Vif-mediated degradation of APOBEC3G RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation Neddylation Regulation of expression of SLITs and ROBOs Inactivation of CSF3 (G-CSF) signaling Inactivation of CSF3 (G-CSF) signaling Antigen processing: Ubiquitination & Proteasome degradation	Ub-specific processing proteases Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS			Adult body size ( 32376654) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		31 interacting genes: ACSM5 ASB11 ASB2 ASB8 CAPN1 CCP110 CDR2 CEBPE DGAT2 ELOA ELOA2 ELOA3P ELOC EPOR GHR GPS1 GPS2 HOXC10 LRRC41 MRPL53 PRAME RACK1 RNF7 SMG1 SOCS1 SOCS3 SOCS6 STC2 USP33 VHL ZYG11B	16 interacting genes: CCP110 CHRM5 DDX56 DIO2 EIF6 ELOB ELOC PRKN SELENBP1 TRIM54 TRIM63 UBC USP15 USP21 USP28 VHL
Entrez ID		6923	23032
HPRD ID		02874	10297
Ensembl ID		ENSG00000103363	ENSG00000077254
Uniprot IDs		A0A384MDL3 Q15370	Q8TEY7
PDB IDs		1LM8 1LQB 1VCB 2C9W 2IZV 2JZ3 2MA9 3DCG 3ZKJ 3ZNG 3ZRC 3ZRF 3ZTC 3ZTD 3ZUN 4AJY 4AWJ 4B95 4B9K 4BKS 4BKT 4N9F 4W9C 4W9D 4W9E 4W9F 4W9G 4W9H 4W9I 4W9J 4W9K 4W9L 4WQO 5BO4 5LLI 5N4W 5NVV 5NVW 5NVX 5NVY 5NVZ 5NW0 5NW1 5NW2 5T35 6BVB 6C5X 6FMI 6FMJ 6FMK 6GFX 6GFY 6GFZ 6GMN 6GMQ 6GMR 6GMX 6HAX 6HAY 6HR2 6I4X 6I5J 6I5N 6I7Q 6I7R 6P59 6R6H 6R7F 6R7H 6R7I 6R7N 6SIS 6V9H 6ZHC 7KHH	2UZG
Enriched GO Terms of Interacting Partners?
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