TBX2 and LZTR1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		TBX2	LZTR1
Description		T-box transcription factor 2	leucine zipper like transcription regulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Golgi Apparatus Endomembrane System Cul3-RING Ubiquitin Ligase Complex Recycling Endosome Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Small GTPase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Heart Looping Outflow Tract Septum Morphogenesis Outflow Tract Morphogenesis Endocardial Cushion Morphogenesis Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Endocardial Cushion Formation Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Muscle Cell Fate Determination Cell Aging Regulation Of Heart Contraction Positive Regulation Of Cell Population Proliferation Embryonic Heart Tube Development Aorta Morphogenesis Atrioventricular Canal Development Embryonic Digit Morphogenesis Negative Regulation Of Transcription, DNA-templated Embryonic Camera-type Eye Morphogenesis Cardiac Muscle Tissue Development Smooth Muscle Cell Differentiation Roof Of Mouth Development Positive Regulation Of Cardiac Muscle Cell Proliferation Pharynx Development Developmental Growth Involved In Morphogenesis Mammary Placode Formation Ureteric Peristalsis Cellular Senescence Negative Regulation Of Heart Looping Negative Regulation Of Cardiac Chamber Formation Cardiac Jelly Development Atrioventricular Canal Morphogenesis	Protein Ubiquitination Negative Regulation Of Ras Protein Signal Transduction
Pathways
Drugs
Diseases
GWAS		Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Chloride levels ( 29403010) Chronic kidney disease ( 20383146) Circulating fibroblast growth factor 23 levels ( 30217807) Corneal hysteresis ( 32716492) Corneal resistance factor ( 32716492) Coronary artery disease ( 29212778) Creatinine levels ( 31015462 20383145) Diastolic blood pressure ( 27841878 27618447 27618448 30487518) Estimated glomerular filtration rate ( 31015462) Height ( 20881960 19893584 18391951) Hypertension ( 27618447 30487518) Kidney volume ( 34128465) Mean arterial pressure ( 26390057 27618448 30487518) Potassium levels ( 29403010) Pulse pressure ( 27841878 27618447) Refractive error ( 32231278) Sitting height ratio ( 25865494) Spontaneous preterm birth without premature rupture of membranes ( 31194736) Systolic blood pressure ( 27841878 28739976 27618447 27618448 30487518) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		12 interacting genes: ATXN1L CEBPE CIDEB CNOT2 CYSRT1 KRTAP6-3 LMO2 LZTR1 MEIS2 NKX2-5 TNPO2 TTC19	55 interacting genes: AATF ANKRD53 ASB12 BMPR1B CEBPZ CHAF1A CNOT6L E2F8 EHMT1 FANK1 GABARAPL2 HCLS1 HDAC4 HRAS IKBKG KDM2B KRAS L3MBTL3 MCM3 MED16 MED7 MYBL2 NR1H3 NRAS PAPOLG PARP1 POLR1B POLR2B POLR2E RAI1 RERE RIT1 RUVBL1 SCMH1 SND1 SP100 SREBF2 SSX4 STAT1 SUGP2 TAF11 TBX2 TCF19 TFAP2B TRIM5 TUBGCP4 WWP1 ZBTB1 ZNF137P ZNF175 ZNF451 ZNF490 ZNF584 ZNF714 ZZZ3
Entrez ID		6909	8216
HPRD ID		02850	08992
Ensembl ID		ENSG00000121068	ENSG00000099949
Uniprot IDs		A0A024QZ86 Q13207	A0A384NL67 Q8N653
PDB IDs
Enriched GO Terms of Interacting Partners?
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