TBCA and AFF1

		TBCA	AFF1
Description		tubulin folding cofactor A	AF4/FMR2 family member 1
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GO Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Microtubule Microtubule Cytoskeleton	Transcription Elongation Factor Complex Super Elongation Complex
	Molecular Function	RNA Binding Protein Binding Tubulin Binding Beta-tubulin Binding Chaperone Binding	Protein Binding
	Biological Process	Protein Folding Tubulin Complex Assembly Post-chaperonin Tubulin Folding Pathway	Regulation Of Gene Expression
Pathways		Post-chaperonin tubulin folding pathway
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494) Platelet distribution width ( 32888494)	Alzheimer's disease (cognitive decline) ( 23535033) Apolipoprotein A1 levels ( 32203549 33730874) Basophil count ( 32888494) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 32888494 27863252) Bulimia nervosa ( 23568457) Diastolic blood pressure ( 28234671) Eyebrow thickness ( 26926045) HDL cholesterol levels ( 32203549 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Heel bone mineral density ( 30598549 28869591) Hematocrit ( 29403010 32888494 27863252) Hematological and biochemical traits ( 31902109) Hemoglobin ( 29403010 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Low density lipoprotein cholesterol levels ( 32154731) Lymphocyte counts ( 32888494) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Mean platelet volume ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Metabolic syndrome ( 31589552) Multiple sclerosis ( 31604244) PR interval ( 32439900) Red blood cell count ( 32888494 27863252) Refractive error ( 32231278) Systemic lupus erythematosus ( 22291604) Total bilirubin levels ( 29403010) Triglyceride levels ( 32203549 32154731 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Triglycerides ( 20864672 30275531 25961943 20686565) White blood cell count (basophil) ( 29403010 27863252)
Interacting Genes		11 interacting genes: AFF1 CDC42 CNTN4 EDIL3 ERBB3 LHFPL2 PAM PHAX RAG1 TAF9 TERF2IP	10 interacting genes: ARFIP1 H3-4 MLLT1 MLLT3 NT5E SASH1 SIAH1 SIAH2 SMAD9 TBCA
Entrez ID		6902	4299
HPRD ID		18166	08871
Ensembl ID		ENSG00000171530	ENSG00000172493
Uniprot IDs		E5RIX8 O75347 Q6FGD7	B4DJU9 P51825 Q14C88
PDB IDs		1H7C	2LM0
Enriched GO Terms of Interacting Partners?
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