TARBP2 and ZMAT3

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		TARBP2	ZMAT3
Description		TARBP2 subunit of RISC loading complex	zinc finger matrin-type 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol RISC Complex Nuclear Body Perinuclear Region Of Cytoplasm RISC-loading Complex	Nucleoplasm Nucleolus Plasma Membrane
	Molecular Function	Double-stranded RNA Binding Protein Binding Enzyme Binding SiRNA Binding MiRNA Binding Pre-mRNA Binding Identical Protein Binding Protein Homodimerization Activity Protein N-terminus Binding Pre-miRNA Binding	RNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Regulation Of Translation Negative Regulation Of Protein Kinase Activity Production Of SiRNA Involved In RNA Interference Targeting Of MRNA For Destruction Involved In RNA Interference Pre-miRNA Processing SiRNA Loading Onto RISC Involved In RNA Interference Production Of MiRNAs Involved In Gene Silencing By MiRNA MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Positive Regulation Of Viral Genome Replication Regulation Of Viral Transcription Negative Regulation Of Defense Response To Virus By Host Regulation Of Production Of SiRNA Involved In RNA Interference Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA	Apoptotic Process Cellular Response To DNA Damage Stimulus Protein Transport Regulation Of Growth Positive Regulation Of Apoptotic Process
Pathways		MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean platelet volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Platelet count ( 27863252) Platelet distribution width ( 32888494) Post-traumatic stress disorder (asjusted for relatedness) ( 23726511) Refractive error ( 32231278)
Interacting Genes		30 interacting genes: ADARB1 AGO2 APP DICER1 EIF2AK2 HDHD2 HSPB1 IKBKG KCNIP3 KRT5 KRT6A MAPK8IP2 MED21 NEDD4L NEUROG1 NF2 NUDT18 OGT PNKP PRKRA RBM14 TCEA2 TCEANC TGIF2 TOP1 TRAF4 VAV2 ZMAT3 ZMAT4 ZNF346	6 interacting genes: APP PRKRA SIAH1 STAU1 SUMO2 TARBP2
Entrez ID		6895	64393
HPRD ID		05446	07343
Ensembl ID		ENSG00000139546	ENSG00000172667
Uniprot IDs		A0A024RB49 Q15633	Q9HA38
PDB IDs		2CPN 3ADL 3LLH 4WYQ 5N8L 5N8M 5ZAK 5ZAL 5ZAM
Enriched GO Terms of Interacting Partners?
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