TACR1 and TAC3

Number of citations of the paper that reports this interaction (PubMedID 12727971)
4

Data Source:
HPRD (in vitro)

		TACR1	TAC3
Description		tachykinin receptor 1	tachykinin precursor 3
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Sperm Flagellum Sperm Head Sperm Midpiece	Extracellular Region Extracellular Space
	Molecular Function	Tachykinin Receptor Activity Protein Binding Substance P Receptor Activity	Signaling Receptor Binding Protein Binding
	Biological Process	Inflammatory Response Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Tachykinin Receptor Signaling Pathway Detection Of Abiotic Stimulus Response To Pain Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Flagellated Sperm Motility	Tachykinin Receptor Signaling Pathway Neuropeptide Signaling Pathway Female Pregnancy Positive Regulation Of Blood Pressure
Pathways		Tachykinin receptors bind tachykinins G alpha (q) signalling events Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Tachykinin receptors bind tachykinins G alpha (q) signalling events
Drugs		Tramadol Aprepitant Ketamine Vapreotide AV608 GW 597599 CP-122721 R673 SR 140333 Casopitant Netupitant Rolapitant Vestipitant Vofopitant Fosnetupitant	Copper
Diseases
GWAS		Bipolar disorder x sex interaction ( 34099189) Brain connectivity ( 23471985) Chronotype ( 30696823) Diisocyanate-induced asthma ( 25918132) Gout ( 32238385) Nonunion in individuals with fractures ( 30680360) Pursuit maintenance gain ( 29064472) Seborrheic dermatitis ( 29203360) Sexual dimorphism in anthropometric traits ( 23754948) Weight ( 28552196)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Menopause (age at onset) ( 26414677) Red cell distribution width ( 28957414) Schizophrenia ( 25056061)
Interacting Genes		7 interacting genes: CCDC167 GPRASP1 GRK5 TAC1 TAC3 TAC4 TMEM147	12 interacting genes: CCDC90B ELP1 FEZ1 GPRASP1 PRB1 PRH1 PTN TACR1 TACR2 TACR3 UBC UBR1
Entrez ID		6869	6866
HPRD ID		01208	08877
Ensembl ID		ENSG00000115353	ENSG00000166863
Uniprot IDs		P25103	A0A024RB47 A0A024RB97 Q9UHF0
PDB IDs		2KS9 2KSA 2KSB 6E59 6HLL 6HLO 6HLP	1P9F
Enriched GO Terms of Interacting Partners?
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