TAC1 and TACR3

Number of citations of the paper that reports this interaction (PubMedID 9272936)
12

Data Source:
BioGRID (pull down)
HPRD (in vivo)

		TAC1	TACR3
Description		tachykinin precursor 1	tachykinin receptor 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Axon Neuronal Cell Body Synapse	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Dendrite Membrane Neuronal Cell Body Membrane Sperm Midpiece
	Molecular Function	Substance P Receptor Binding	Tachykinin Receptor Activity Protein Binding
	Biological Process	Positive Regulation Of Acute Inflammatory Response Inflammatory Response Positive Regulation Of Cytosolic Calcium Ion Concentration Tachykinin Receptor Signaling Pathway Neuropeptide Signaling Pathway Cell-cell Signaling Chemical Synaptic Transmission Insemination Long-term Memory Regulation Of Blood Pressure Associative Learning Detection Of Abiotic Stimulus Response To Hormone Negative Regulation Of Heart Rate Positive Regulation Of Epithelial Cell Migration Sensory Perception Of Pain Positive Regulation Of Synaptic Transmission, Cholinergic Positive Regulation Of Synaptic Transmission, GABAergic Response To Lipopolysaccharide Positive Regulation Of Renal Sodium Excretion Response To Morphine Positive Regulation Of Action Potential Positive Regulation Of Ossification Positive Regulation Of Saliva Secretion Response To Pain Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Stress Fiber Assembly Cellular Response To Nerve Growth Factor Stimulus Positive Regulation Of Corticosterone Secretion	Tachykinin Receptor Signaling Pathway Aging Positive Regulation Of Heart Rate Response To Estradiol Regulation Of Dopamine Metabolic Process Response To Cocaine Hyperosmotic Salinity Response Response To Morphine Positive Regulation Of Blood Pressure Regulation Of Feeding Behavior Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Flagellated Sperm Motility
Pathways		Tachykinin receptors bind tachykinins G alpha (q) signalling events	Tachykinin receptors bind tachykinins G alpha (q) signalling events
Drugs			Osanetant Talnetant Pavinetant
Diseases
GWAS		Adventurousness ( 30643258) Adverse response to radiation therapy ( 23719583) Blood protein levels ( 30072576) Feeling nervous ( 29500382) General risk tolerance (MTAG) ( 30643258) Regular attendance at a religious group ( 29970889) Response to platinum-based agents ( 22020760) Squamous cell lung carcinoma ( 28604730)	Chronotype ( 30696823) Heel bone mineral density ( 30598549) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Menarche (age at onset) ( 27182965 25231870) Rosacea symptom severity ( 29771307) Spontaneous preterm birth without premature rupture of membranes ( 31194736)
Interacting Genes		12 interacting genes: ARHGEF40 BAG6 CDK6 CENPB FN1 MEP1A PREP SGCE TACR1 TACR2 TACR3 XRCC6	5 interacting genes: GPRASP1 PALS2 TAC1 TAC3 TAC4
Entrez ID		6863	6870
HPRD ID		08876	01209
Ensembl ID		ENSG00000006128	ENSG00000169836
Uniprot IDs		P20366 Q9Y494	P29371
PDB IDs		2B19 2KS9 2KSA 2KSB 4HOM
Enriched GO Terms of Interacting Partners?
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