VAMP1 and SGMS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		VAMP1	SGMS2
Description		vesicle associated membrane protein 1	sphingomyelin synthase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane SNARE Complex Azurophil Granule Membrane Specific Granule Membrane Neuron Projection Tertiary Granule Membrane	Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Golgi Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	Ceramide Phosphoethanolamine Synthase Activity Protein Binding Kinase Activity Sphingomyelin Synthase Activity Ceramide Cholinephosphotransferase Activity
	Biological Process	Vesicle Fusion SNARE Complex Assembly	Sphingomyelin Biosynthetic Process Phosphorylation Sphingolipid Biosynthetic Process Regulation Of Bone Mineralization Ceramide Biosynthetic Process Ceramide Phosphoethanolamine Biosynthetic Process
Pathways		Toxicity of botulinum toxin type D (botD) Toxicity of botulinum toxin type F (botF) Toxicity of botulinum toxin type G (botG)	Sphingolipid de novo biosynthesis
Drugs		Botulinum Toxin Type B
Diseases
GWAS		Hip geometry ( 17903296)	Metabolite levels ( 23823483) Monoclonal gammopathy of undetermined significance ( 30737484) Obsessive-compulsive traits ( 33531474)
Interacting Genes		36 interacting genes: AQP6 ARL13B BCAP31 CDKN2A CRB3 CREB3L1 CYB5R3 DNAJC5 EBP ELOVL4 ELOVL7 ERGIC3 FAM210B FCER1G GPR152 KASH5 LAPTM5 LMNA REEP4 RETREG3 RNF24 SCN3B SEC11C SGMS2 SLC30A8 SNAP23 SNAP29 STX1A STX1B STX4 TMEM101 TMEM14B TMEM35A TMX2 VAPA VAPB	6 interacting genes: CTSA GPX8 LMNA LPAR3 VAMP1 ZFPL1
Entrez ID		6843	166929
HPRD ID		01716	11323
Ensembl ID		ENSG00000139190	ENSG00000164023
Uniprot IDs		F5GZV7 P23763	A0A024RDH4 Q8NHU3
PDB IDs
Enriched GO Terms of Interacting Partners?
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