STXBP1 and NEFH

Number of citations of the paper that reports this interaction (PubMedID 12963086)
15

Data Source:
HPRD (in vivo)

		STXBP1	NEFH
Description		syntaxin binding protein 1	neurofilament heavy chain
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol Cytoskeleton Plasma Membrane Secretory Granule Axon Platelet Alpha Granule Protein-containing Complex Phagocytic Vesicle Perinuclear Region Of Cytoplasm Presynaptic Active Zone Membrane Extracellular Exosome Postsynapse Glutamatergic Synapse	Cytoplasm Cytoskeleton Neurofilament Postsynaptic Density Axon Neurofibrillary Tangle Schaffer Collateral - CA1 Synapse Postsynaptic Intermediate Filament Cytoskeleton
	Molecular Function	SNARE Binding RNA Binding Protein Binding Syntaxin-1 Binding Protein Kinase Binding Protein Domain Specific Binding Syntaxin Binding Identical Protein Binding Phospholipase Binding Protein N-terminus Binding	Structural Constituent Of Cytoskeleton Protein Binding Microtubule Binding Kinesin Binding Protein Kinase Binding Protein-macromolecule Adaptor Activity Dynein Complex Binding Structural Constituent Of Postsynaptic Intermediate Filament Cytoskeleton
	Biological Process	Platelet Degranulation Developmental Process Involved In Reproduction Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Neurotransmitter Secretion Neuromuscular Synaptic Transmission Axon Target Recognition Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Priming Synaptic Vesicle Maturation Vesicle-mediated Transport Negative Regulation Of Protein-containing Complex Assembly Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Negative Regulation Of Synaptic Transmission, GABAergic Response To Estradiol SNARE Complex Assembly Regulation Of SNARE Complex Assembly Positive Regulation Of Mast Cell Degranulation Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Calcium Ion-dependent Exocytosis Protein Stabilization Long-term Synaptic Depression Platelet Aggregation Cellular Response To Interferon-gamma Protein Localization To Plasma Membrane Presynaptic Dense Core Vesicle Exocytosis Positive Regulation Of Vesicle Docking Positive Regulation Of Glutamate Secretion, Neurotransmission Regulation Of Acrosomal Vesicle Exocytosis	Microtubule Cytoskeleton Organization Axonogenesis Cell Projection Assembly Neurofilament Bundle Assembly Peripheral Nervous System Neuron Axonogenesis Neurofilament Cytoskeleton Organization Axon Development Postsynaptic Intermediate Filament Cytoskeleton Organization Regulation Of Organelle Transport Along Microtubule Cellular Response To Leukemia Inhibitory Factor
Pathways		Regulation of insulin secretion Neurexins and neuroligins
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Whole brain grey matter density ( 31530798)
Interacting Genes		35 interacting genes: APBA1 APBA2 APP BRME1 CDK5 CDK5R1 CENPP DOC2A DOC2B HGS MAPK1 MAPT MEOX2 MTDH MTNR1A NEFH NEFM PLD1 PLD2 PRKCA PRKCB PRKCG SPICE1 SPTBN1 SQSTM1 STOM STX19 STX1A STX1B STX2 STX3 STX5 SYTL4 TRIM38 USO1	6 interacting genes: ERBB2 MAPK1 NEFL NEFM PKN1 STXBP1
Entrez ID		6812	4744
HPRD ID		04235	01204
Ensembl ID		ENSG00000136854	ENSG00000100285
Uniprot IDs		P61764	P12036
PDB IDs		6L03
Enriched GO Terms of Interacting Partners?
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