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STX4 and SNAP25
Number of citations of the paper that reports this interaction (PubMedID
9852078
)
74
Data Source:
BioGRID
(pull down)
HPRD
(in vitro, two hybrid)
STX4
SNAP25
Description
syntaxin 4
synaptosome associated protein 25
Image
No pdb structure
GO Annotations
Cellular Component
Storage Vacuole
Extracellular Space
Endosome
Vacuole
Trans-Golgi Network
Cytosol
Plasma Membrane
Synaptic Vesicle
Cell Surface
Endomembrane System
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Lamellipodium
Phagocytic Vesicle Membrane
SNARE Complex
Neuron Projection Membrane
Myelin Sheath Adaxonal Region
Somatodendritic Compartment
Specific Granule
Dendritic Spine
Lateral Loop
Synapse
Perinuclear Region Of Cytoplasm
Presynaptic Active Zone Membrane
Extracellular Exosome
Postsynapse
Glutamatergic Synapse
Photoreceptor Inner Segment
Cytoplasm
Trans-Golgi Network
Cytosol
Cytoskeleton
Plasma Membrane
Synaptic Vesicle
Membrane
Growth Cone
SNARE Complex
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Vesicle
Specific Granule Membrane
Somatodendritic Compartment
Presynaptic Membrane
Neuron Projection
Perinuclear Region Of Cytoplasm
Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex
Tertiary Granule Membrane
Postsynapse
Glutamatergic Synapse
Molecular Function
SNARE Binding
SNAP Receptor Activity
Protein Binding
Sphingomyelin Phosphodiesterase Activator Activity
Voltage-gated Potassium Channel Activity
SNAP Receptor Activity
Protein Binding
Syntaxin-1 Binding
Syntaxin Binding
Calcium-dependent Protein Binding
Biological Process
Positive Regulation Of Immunoglobulin Production
Intracellular Protein Transport
Exocytosis
Vesicle Fusion
Positive Regulation Of Cell Population Proliferation
Regulation Of Exocytosis
Positive Regulation Of Cell Migration
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Protein Localization To Cell Surface
Cellular Response To Oxidative Stress
SNARE Complex Assembly
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Positive Regulation Of Catalytic Activity
Positive Regulation Of Eosinophil Degranulation
Positive Regulation Of Cell Adhesion
Vesicle Docking
Organelle Fusion
Positive Regulation Of Chemotaxis
Long-term Synaptic Potentiation
Cellular Response To Interferon-gamma
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Protein Localization To Plasma Membrane
Cornified Envelope Assembly
Positive Regulation Of Protein Localization To Cell Surface
Neurotransmitter Uptake
Exocytosis
Vesicle Fusion
Chemical Synaptic Transmission
Locomotory Behavior
Associative Learning
Regulation Of Neuron Projection Development
Synaptic Vesicle Exocytosis
Synaptic Vesicle Docking
Synaptic Vesicle Priming
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Regulation Of Insulin Secretion
Long-term Synaptic Potentiation
Potassium Ion Transmembrane Transport
Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane
Neurotransmitter Receptor Internalization
Pathways
Disinhibition of SNARE formation
ER-Phagosome pathway
Translocation of SLC2A4 (GLUT4) to the plasma membrane
trans-Golgi Network Vesicle Budding
Other interleukin signaling
Serotonin Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Regulation of insulin secretion
Other interleukin signaling
Toxicity of botulinum toxin type A (botA)
Toxicity of botulinum toxin type C (botC)
Toxicity of botulinum toxin type E (botE)
Neutrophil degranulation
GABA synthesis, release, reuptake and degradation
Sensory processing of sound by inner hair cells of the cochlea
Drugs
Botulinum toxin type A
Diseases
GWAS
Response to metformin (IC50) (
28173075
)
Triglyceride levels (
32203549
)
Brain imaging measurements (variance) (
32047264
)
Cardiac hypertrophy (
21348951
)
Psychosis proneness (hypomanic personality scale and revised social anhedonia scale) (
28525603
)
Interacting Genes
71 interacting genes:
ABI2
ACTB
ANKRD46
BET1
CYBRD1
DLG1
DNAJC5
FAXDC2
GIMAP5
GOSR2
GPR152
ITSN2
LLGL1
LMNA
NAPA
NAPB
NSF
PLP1
PSMA3
RAB11A
RAB4A
RAB5A
RNF4
SCRIB
SEC22A
SEC22B
SEPTIN5
SERP1
SGPL1
SH3GLB2
SNAP23
SNAP25
SNAP29
SNAP47
STX10
STX11
STX12
STX16
STX1A
STX1B
STX2
STX3
STX5
STX6
STX7
STX8
STXBP3
STXBP4
STXBP5
STXBP6
SYT1
SYT4
SYT7
TCEANC
TMEM199
TMEM203
TRAF3IP3
TXLNA
TXLNB
TXLNG
USE1
VAMP1
VAMP2
VAMP3
VAMP4
VAMP5
VAMP7
VAMP8
VAPB
VTI1B
ZFPL1
39 interacting genes:
APP
CENPF
CPLX1
DNM1
FBXO7
GOSR1
HGS
ITSN1
KCNB1
KIF5B
NAPA
PRKACA
PRKCA
PRRT2
RIMS1
SCAMP1
SNAPIN
SRCIN1
STX11
STX12
STX19
STX1A
STX2
STX3
STX4
STX5
STXBP6
SYT1
SYT3
SYT9
TRIM9
UQCC2
VAMP2
VAMP7
VAMP8
WASHC3
ZDHHC17
ZNF177
ZNF559-ZNF177
Entrez ID
6810
6616
HPRD ID
01722
02637
Ensembl ID
ENSG00000103496
ENSG00000132639
Uniprot IDs
B7Z425
Q12846
P60880
PDB IDs
1KIL
1XTG
2N1T
3DDA
3DDB
3RK2
3RK3
3RL0
3ZUR
5W7I
5W7J
6JLH
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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