SULT1E1 and PDE9A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SULT1E1	PDE9A
Description		sulfotransferase family 1E member 1	phosphodiesterase 9A
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Nuclear Membrane	Nucleoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Plasma Membrane Ruffle Membrane Sarcolemma Perikaryon Perinuclear Region Of Cytoplasm
	Molecular Function	Aryl Sulfotransferase Activity Estrone Sulfotransferase Activity Steroid Binding Protein Binding Sulfotransferase Activity Flavonol 3-sulfotransferase Activity Steroid Sulfotransferase Activity	3',5'-cyclic-nucleotide Phosphodiesterase Activity Protein Binding Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity
	Biological Process	Ethanol Catabolic Process Estrogen Catabolic Process Steroid Metabolic Process Estrogen Metabolic Process Positive Regulation Of Fat Cell Differentiation 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation	Signal Transduction Positive Regulation Of Cardiac Muscle Hypertrophy CGMP-mediated Signaling CGMP Metabolic Process CGMP Catabolic Process
Pathways		Cytosolic sulfonation of small molecules	cGMP effects
Drugs		Cyclizine Adenosine 3',5'-diphosphate 3'-phospho-5'-adenylyl sulfate 3,3',5,5'-tetrachlorobiphenyl-4,4'-diol	Caffeine gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine 3-isobutyl-1-methyl-7H-xanthine Trapidil
Diseases
GWAS		Heel bone mineral density ( 30598549)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Perceived unattractiveness to mosquitoes ( 28199695)
Interacting Genes		13 interacting genes: BMPR2 COPS6 EEF1A1 ENOX1 ERG28 IGSF21 LRIF1 PDE9A RBM48 SETDB1 SULT2B1 TP53 UNC119	41 interacting genes: BAG3 CDC37 CLK1 CRY2 CYSRT1 ERG FXR1 FXR2 GORASP2 IQCB1 KANK2 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP4-2 KRTAP5-9 KRTAP9-2 LAGE3 LINC02913 LMO2 MX1 NAA38 NFIL3 NOTCH2NLA PCNT PHYHIPL PRPF18 SDCBP SULT1E1 TFAP4 TRIM32 TRPV6 UBD UTP23 WDR5
Entrez ID		6783	5152
HPRD ID		08966	09115
Ensembl ID		ENSG00000109193	ENSG00000160191
Uniprot IDs		P49888 Q53X91	A0A0S2Z475 A0A0S2Z4A3 A0A0S2Z4T6 O76083
PDB IDs		1G3M 1HY3 4JVL 4JVM 4JVN	2HD1 2YY2 3DY8 3DYL 3DYN 3DYQ 3DYS 3JSI 3JSW 3K3E 3K3H 3N3Z 3QI3 3QI4 4E90 4G2J 4G2L 4GH6 4Y86 4Y87 4Y8C 6A3N 6LZZ
Enriched GO Terms of Interacting Partners?
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