SSR1 and SERPINF2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		SSR1	SERPINF2
Description		signal sequence receptor subunit 1	serpin family F member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Extracellular Region Fibrinogen Complex Extracellular Space Cell Surface Platelet Alpha Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	Protein Binding	Protease Binding Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Cotranslational Protein Targeting To Membrane Positive Regulation Of Cell Population Proliferation	Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Acute-phase Response Negative Regulation Of Plasminogen Activation Negative Regulation Of Endopeptidase Activity Collagen Fibril Organization Positive Regulation Of Collagen Biosynthetic Process Fibrinolysis Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of JNK Cascade Blood Vessel Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Fibrinolysis Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Transforming Growth Factor Beta Production Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Pathways		SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes	Platelet degranulation Dissolution of Fibrin Clot
Drugs			Ocriplasmin Copper
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Ewing sarcoma ( 30093639) Hip circumference adjusted for BMI ( 34021172) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 24509480 32499647 30718926 28869590)	Blood protein levels ( 29875488) Calcium levels ( 24068962 20705733) Hodgkin's lymphoma ( 34216518) Serum albumin level ( 23022100 29403010) Urate levels ( 31578528)
Interacting Genes		9 interacting genes: DKC1 EEF1A1 HSPA13 NPC2 NUP54 ODC1 PTN SERPINF2 UTP14A	18 interacting genes: BCAP31 CFD CTRB1 DEFA1 ELANE F11 F13A1 FGA KLK13 KLK2 KLK6 MYH10 PLAU PLG PRSS1 SERPINB12 SSR1 TGM2
Entrez ID		6745	5345
HPRD ID		02924	02029
Ensembl ID		ENSG00000124783	ENSG00000167711
Uniprot IDs		C9JBX5 P43307	P08697
PDB IDs
Enriched GO Terms of Interacting Partners?
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