SRP19 and SRP54

Number of citations of the paper that reports this interaction (PubMedID 26344197)
178

Data Source:
BioGRID (biochemical)
HPRD (in vitro)

		SRP19	SRP54
Description		signal recognition particle 19	signal recognition particle 54
Image
GO Annotations	Cellular Component	Nucleolus Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Signal Recognition Particle	Nucleus Nucleolus Cytoplasm Endoplasmic Reticulum Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Nuclear Speck
	Molecular Function	RNA Binding Protein Binding 7S RNA Binding Ribosome Binding	RNA Binding GTPase Activity Protein Binding GTP Binding 7S RNA Binding GDP Binding Endoplasmic Reticulum Signal Peptide Binding Ribonucleoprotein Complex Binding
	Biological Process	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition	SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Neutrophil Chemotaxis Granulocyte Differentiation Exocrine Pancreas Development Protein Targeting To ER
Pathways		SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane	SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS			Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Immunoglobulin light chain (AL) amyloidosis ( 28025584)
Interacting Genes		10 interacting genes: AP3S1 APP ATG12 IPO5 IPO7 IPO8 KPNA1 MAPK8IP2 SRP54 TNPO1	9 interacting genes: EGLN3 KLK12 OGT PRORP RALGAPA1 RNPS1 SRP19 STAB1 TKTL1
Entrez ID		6728	6729
HPRD ID		01644	05330
Ensembl ID		ENSG00000153037	ENSG00000100883
Uniprot IDs		A0A087WYR0 A0A2U3TZN1 P09132	G3V480 P61011
PDB IDs		1JID 1MFQ 1RY1 2J37 3KTV 4P3E 5M73	1MFQ 1QB2 5L3Q 6Y2Z 6Y30 6Y31 6Y32
Enriched GO Terms of Interacting Partners?
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