SNRPF and GEMIN5

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, pull down)

		SNRPF	GEMIN5
Description		small nuclear ribonucleoprotein polypeptide F	gem nuclear organelle associated protein 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U7 SnRNP U1 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Body SMN Complex SMN-Gemin2 Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies
	Molecular Function	RNA Binding Protein Binding	RNA 7-methylguanosine Cap Binding RNA Binding MRNA 3'-UTR Binding Protein Binding SnRNA Binding U1 SnRNA Binding U4 SnRNA Binding U4atac SnRNA Binding Ribosome Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Translation Regulation Of Translation Protein-containing Complex Assembly
Pathways		SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	snRNP Assembly
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561) Lung function (FEV1/FVC) ( 30804560) Peak expiratory flow ( 30804560) Refractive error ( 32231278) Vitamin C levels ( 33203707)	Venous thromboembolism ( 32232851)
Interacting Genes		26 interacting genes: COIL DDX20 GEMIN5 GEMIN6 HOMER3 HSPB1 IKZF1 IL7R LNX1 LSM3 LSM5 LSM6 LSM7 MEOX2 NSD1 OSBPL2 PSMA3 PUF60 RPL9 SMN2 SNRPD2 SNRPE SNRPG SRRT SRSF5 WDR77	23 interacting genes: CLK1 DDX20 EIF4E GALNT10 GEMIN2 GEMIN4 MAP2K4 MAP3K5 MAPK8 RN7SL1 RNU1-1 RNU2-1 SLC27A2 SMN1 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG STXBP3 SUMO2
Entrez ID		6636	25929
HPRD ID		04645	06109
Ensembl ID		ENSG00000139343	ENSG00000082516
Uniprot IDs		P62306	B7ZLC9 Q58EZ8 Q8TEQ6
PDB IDs		3CW1 3JCR 3PGW 4F7U 4PJO 4V98 4WZJ 5MQF 5O9Z 5XJC 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU 5YZG 5Z56 5Z57 5Z58 6AH0 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6V4X 6Y53 6Y5Q 7A5P 7ABG 7ABI 7B0Y	5GXH 5GXI 5H1J 5H1K 5H1L 5H1M 5H3S 5H3T 5H3U 5TEE 5TEF 5THA 6RNQ 6RNS
Enriched GO Terms of Interacting Partners?
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