SLN and SYNE4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		SLN	SYNE4
Description		sarcolipin	spectrin repeat containing nuclear envelope family member 4
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GO Annotations	Cellular Component	Integral Component Of Membrane Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Enzyme Inhibitor Activity Protein Binding ATPase Binding	Protein Binding
	Biological Process	Calcium Ion Transport Negative Regulation Of Catalytic Activity Negative Regulation Of Protein-containing Complex Disassembly Regulation Of Calcium Ion Transport Sarcoplasmic Reticulum Calcium Ion Transport Negative Regulation Of Calcium Ion Import Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Relaxation Of Muscle Negative Regulation Of Calcium Ion Binding Positive Regulation Of Protein Depolymerization Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity	Establishment Of Epithelial Cell Apical/basal Polarity
Pathways		Ion homeostasis Ion transport by P-type ATPases
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: ATP2A1 DDX10 KASH5 LMNA PLN PTPN11 SYNE4 TMEM79	57 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B WDR62 ZNF250 ZNF648
Entrez ID		6588	163183
HPRD ID		03729	08776
Ensembl ID		ENSG00000170290	ENSG00000181392
Uniprot IDs		A0A158RFT9 O00631	Q8N205
PDB IDs		1JDM	6R16 6WMD
Enriched GO Terms of Interacting Partners?
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