SLC10A2 and IFITM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC10A2	IFITM3
Description		solute carrier family 10 member 2	interferon induced transmembrane protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Early Endosome Membrane Late Endosome Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Bile Acid:sodium Symporter Activity	Protein Binding
	Biological Process	Sodium Ion Transport Bile Acid And Bile Salt Transport Transmembrane Transport	Immune Response Response To Virus Negative Regulation Of Viral Transcription Response To Interferon-gamma Response To Interferon-alpha Response To Interferon-beta Negative Regulation Of Viral Genome Replication Negative Regulation Of Viral Entry Into Host Cell Defense Response To Virus Type I Interferon Signaling Pathway
Pathways		Recycling of bile acids and salts	Interferon alpha/beta signaling
Drugs		Volixibat
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) epithelial cell adhesion molecule levels ( 25147954) Esophageal cancer (alcohol interaction) ( 22960999) Gallstone disease ( 30504769) Late-onset Alzheimer's disease ( 27770636) Metabolite levels ( 23823483) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Response to quetiapine in schizophrenia ( 29503163) Serum metabolite levels ( 33031748) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Eosinophil counts ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252)
Interacting Genes		11 interacting genes: C3orf52 C5 CCL4L2 CTXN3 EFNA5 IFITM3 NRM PSENEN TEX264 TMEM222 UPK1B	27 interacting genes: ABHD16A AQP6 CD53 ELOVL2 ERGIC3 FAM210B FFAR2 FKBP7 GLP1R GPR37 GPRC5D KIR2DL3 LYPD5 MS4A3 NEDD4 OPRM1 PLP1 PTAFR REEP4 RETREG3 SGPL1 SLC10A1 SLC10A2 SLC16A7 TMEM14B TMEM86B VKORC1
Entrez ID		6555	10410
HPRD ID		03189	05719
Ensembl ID		ENSG00000125255	ENSG00000142089
Uniprot IDs		Q12908	Q01628
PDB IDs
Enriched GO Terms of Interacting Partners?
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