SLC9A3 and MAST2

Number of citations of the paper that reports this interaction (PubMedID 16159897)
9

Data Source:
HPRD (in vitro, in vivo)

		SLC9A3	MAST2
Description		solute carrier family 9 member A3	microtubule associated serine/threonine kinase 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Brush Border Cell Surface Integral Component Of Membrane Apical Plasma Membrane Brush Border Membrane Extracellular Exosome	Cytoplasm Plasma Membrane Microtubule Cytoskeleton
	Molecular Function	Protein Binding Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity PDZ Domain Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Phosphatase Binding Protein Serine Kinase Activity
	Biological Process	Ion Transport Regulation Of Intracellular PH Potassium Ion Transmembrane Transport Anion Transmembrane Transport Sodium Ion Import Across Plasma Membrane Proton Transmembrane Transport	Protein Phosphorylation Cytoskeleton Organization Peptidyl-serine Phosphorylation Regulation Of Interleukin-12 Production Intracellular Signal Transduction Spermatid Differentiation
Pathways		Sodium/Proton exchangers
Drugs		Tenapanor
Diseases
GWAS		Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Estimated glomerular filtration rate ( 31152163) Lung disease severity in cystic fibrosis ( 26417704) Ulcerative colitis ( 28067908 23128233)	Blood protein levels ( 28240269) Body mass index ( 25673413) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Granulocyte count ( 27863252) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Iron status biomarkers (total iron binding capacity) ( 28334935) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Red blood cell count ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Serum metabolite levels ( 33031748) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Sum basophil neutrophil counts ( 27863252) Type 2 diabetes ( 32499647)
Interacting Genes		9 interacting genes: ADCY2 CHP1 CHP2 LRP2 MAST2 PDZK1 SHANK2 SLC9A3R1 SLC9A3R2	29 interacting genes: ACE2 ACTN2 APP CD200 CD48 CDHR2 DYNLL1 IPO13 KDM4A MXRA7 PTEN RPS27A RPS6KA1 SH3GL2 SLC34A1 SLC9A3 SMN1 SNTB2 SRPK2 STK36 SUMO2 TK1 TPM1 TPM2 TPM3 TRAF2 TRAF6 TTN ZNF417
Entrez ID		6550	23139
HPRD ID		01660	11294
Ensembl ID		ENSG00000066230	ENSG00000086015
Uniprot IDs		P48764	A0A669KBJ4 Q6P0Q8
PDB IDs			2KQF 2KYL
Enriched GO Terms of Interacting Partners?
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