SLC6A8 and CHRM5

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		SLC6A8	CHRM5
Description		solute carrier family 6 member 8	cholinergic receptor muscarinic 5
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Dendrite Synapse Postsynaptic Membrane
	Molecular Function	Molecular_function Creatine Transmembrane Transporter Activity Creatine:sodium Symporter Activity	Phosphatidylinositol Phospholipase C Activity G Protein-coupled Serotonin Receptor Activity Protein Binding G Protein-coupled Acetylcholine Receptor Activity Neurotransmitter Receptor Activity
	Biological Process	Creatine Metabolic Process Neurotransmitter Transport Muscle Contraction Creatine Transmembrane Transport Sodium Ion Transmembrane Transport Nitrogen Compound Transport	Gastric Acid Secretion G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Chemical Synaptic Transmission Dopamine Transport Transmission Of Nerve Impulse Regulation Of Phosphatidylinositol Dephosphorylation G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways		Creatine metabolism	Muscarinic acetylcholine receptors G alpha (q) signalling events
Drugs		Creatine Phosphocreatine	Ziprasidone Amitriptyline Metixene Terfenadine Clozapine Doxylamine Trihexyphenidyl Loxapine Meperidine Imipramine Darifenacin Nortriptyline Amoxapine Cinnarizine Atropine Nicardipine Paroxetine Homatropine methylbromide Trimipramine Scopolamine Benzquinamide Propiomazine Brompheniramine Maprotiline Methantheline Tolterodine Promethazine Doxepin Desipramine Ketamine Quetiapine Aripiprazole Chlorprothixene Methotrimeprazine Tiotropium Solifenacin ALKS 27 Fesoterodine Aclidinium Umeclidinium Dosulepin Etoperidone Homatropine Thonzylamine Revefenacin Propiverine Rociverine Aripiprazole lauroxil
Diseases
GWAS			Malaria ( 31844061)
Interacting Genes		4 interacting genes: BDKRB1 CD59 CHRM5 TAFAZZIN	32 interacting genes: ASPH ASTN2 ATP2A2 ATP9A CBFB CD82 EPB41L1 EPC1 ERCC1 GJB6 GOLGA8A GPRASP1 HLA-F MAP3K1 MSMO1 MYH7 NLE1 NPAS3 PRSS16 REEP5 RGS7 RTN1 SCAND2P SLC2A6 SLC5A6 SLC6A8 SMAD6 SNCA SPNS1 STARD3NL TMEM161A USP33
Entrez ID		6535	1133
HPRD ID		02073	00331
Ensembl ID		ENSG00000130821	ENSG00000184984
Uniprot IDs		P48029 Q59EV7 X5D9C4	A0A024R9I2 P08912 Q8IVW0
PDB IDs			6OL9
Enriched GO Terms of Interacting Partners?
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