SLC6A1 and ARFGAP1

Number of citations of the paper that reports this interaction (PubMedID 19020038)
21

Data Source:
BioGRID (pull down)

		SLC6A1	ARFGAP1
Description		solute carrier family 6 member 1	ADP ribosylation factor GTPase activating protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Axon Neuron Projection Neuronal Cell Body GABA-ergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane	Golgi Membrane Cytosol Synapse
	Molecular Function	Gamma-aminobutyric Acid:sodium Symporter Activity Protein Binding Gamma-aminobutyric Acid Transmembrane Transporter Activity Sodium:chloride Symporter Activity Identical Protein Binding Metal Ion Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Chemical Synaptic Transmission Memory Associative Learning Response To Toxic Substance Response To Sucrose Response To Inorganic Substance Response To Lead Ion Positive Regulation Of Gamma-aminobutyric Acid Secretion Response To Purine-containing Compound Negative Regulation Of Synaptic Transmission, GABAergic Response To Estradiol Sodium Ion Transmembrane Transport Response To Cocaine Synapse Organization Response To Calcium Ion Gamma-aminobutyric Acid Reuptake Gamma-aminobutyric Acid Import Inorganic Anion Import Across Plasma Membrane Sodium Ion Import Across Plasma Membrane Transport Across Blood-brain Barrier Chloride Transmembrane Transport	Protein Transport Vesicle-mediated Transport Regulation Of Endocytosis Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity
Pathways		Na+/Cl- dependent neurotransmitter transporters Reuptake of GABA	XBP1(S) activates chaperone genes COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Clathrin-mediated endocytosis
Drugs		Tiagabine Guvacine
Diseases
GWAS		Body fat percentage ( 31752434) Conduct disorder (maternal expressed emotions interaction) ( 18846501) Loneliness (linear analysis) ( 27629369) Longitudinal alcohol consumption ( 26081443) Lung function ( 31902109) Refractive error ( 32231278) Response to Vitamin E supplementation ( 22437554)
Interacting Genes		6 interacting genes: ARFGAP1 DRD2 HSF2BP HTR6 OXNAD1 STX1A	36 interacting genes: AGTR1 APOB APOC3 APOE APP ARF1 ASB10 COPA COPS5 CSNK1D CYTH2 FOS GABARAPL2 GGCX GRN HRAS KDELR1 KRTAP10-9 KRTAP3-2 KRTAP9-2 LRRK2 MAP1LC3B MED27 PRKACB RAB23 RABGAP1L RASIP1 REEP5 RFC3 RGS2 RPL11 SLC6A1 SMN1 TK1 TMED2 TRIM23
Entrez ID		6529	55738
HPRD ID		00664	06443
Ensembl ID		ENSG00000157103	ENSG00000101199
Uniprot IDs		A0A024R2K8 A0A2R8Y4I3 B7Z3C5 P30531	Q53F62 Q8N6T3
PDB IDs			3DWD 3O47
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?