MRPL44 and NGEF

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		MRPL44	NGEF
Description		mitochondrial ribosomal protein L44	neuronal guanine nucleotide exchange factor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Plasma Membrane Nuclear Body	Cytosol Membrane Growth Cone
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Ribonuclease III Activity Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	RRNA Catabolic Process Mitochondrial Translational Elongation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Nervous System Development Cell Differentiation Regulation Of GTPase Activity Ephrin Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Dendritic Spine Morphogenesis Activation Of GTPase Activity
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	NRAGE signals death through JNK EPHA-mediated growth cone collapse EPHA-mediated growth cone collapse G alpha (12/13) signalling events RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS			Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Contrast sensitivity ( 24152035) Heel bone mineral density ( 30598549 28869591) Parkinson's disease ( 32201043) Pursuit maintenance gain ( 29064472) Schizophrenia ( 28991256 25056061 29483656 30285260 23974872) Sudden cardiac arrest ( 30169657) Superior temporal sulcus banks volume ( 31530798)
Interacting Genes		15 interacting genes: ABI2 CEP70 DGKE IMMT ITFG1 NGEF PI4KA PLPP2 PTN SEMA5B SETDB1 SHC1 USP22 VIM ZNF235	18 interacting genes: ATP5F1C C7orf25 C8orf33 EPHA4 FAM118B HCK MRPL44 NUDT21 RHOA SEPTIN2 SH2D1A SMO TAF1D TRIM55 TRIM63 TTK USP25 YIPF3
Entrez ID		65080	25791
HPRD ID		14763	10442
Ensembl ID		ENSG00000135900	ENSG00000066248
Uniprot IDs		A1MA90 Q9H9J2	B4DDI2 Q8N5V2
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?