SIX1 and EYA1

  • Number of citations of the paper that reports this interaction (PubMedID 28514442)
  • 406
  • Data Source:
  • BioGRID (affinity chromatography technology, two hybrid)
  • HPRD (in vivo, in vitro, two hybrid)

SIX1

EYA1

Description SIX homeobox 1 EYA transcriptional coactivator and phosphatase 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adolescent idiopathic scoliosis ( 30395268)
  • Alanine aminotransferase levels ( 33547301 34315874)
  • Aspartate aminotransferase levels ( 33547301 34315874)
  • Bell's palsy ( 33602968)
  • Chin dimples ( 27182965)
  • Chronic obstructive pulmonary disease-related biomarkers ( 23144326)
  • Heel bone mineral density ( 30598549 28869591)
  • Hypospadias ( 25108383)
  • Longevity (85 years and older) ( 24688116)
  • Paneth cell defects in Crohn's disease ( 28352666)
  • Sleep-related phenotypes ( 17903308)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes 15 interacting genes: CCDC85B DACH1 EYA1 EYA2 EYA3 EYA4 H2AP MDFI PLEKHG4 POU6F2 REL TLE1 TLE3 TLE5 VTN 9 interacting genes: DACH1 GNAI2 GNAZ GSK3B H2AX NDUFB9 SIX1 SIX2 SIX3
Entrez ID 6495 2138
HPRD ID 03125 03388
Ensembl ID ENSG00000126778 ENSG00000104313
Uniprot IDs Q15475 A0A024R813 A0A2R8Y6K4 A6NCB9 B3KXR1 F8WB53 Q0P517 Q99502
PDB IDs 4EGC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?