MTARC1 and EPHB6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MTARC1	EPHB6
Description		mitochondrial amidoxime reducing component 1	EPH receptor B6
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane Nitric-oxide Synthase Complex	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection Receptor Complex
	Molecular Function	Protein Binding Nitrate Reductase Activity Oxidoreductase Activity, Acting On Other Nitrogenous Compounds As Donors Molybdenum Ion Binding Pyridoxal Phosphate Binding Molybdopterin Cofactor Binding Nitrite Reductase (NO-forming) Activity Nitrite Reductase Activity	Transmembrane Receptor Protein Tyrosine Kinase Activity Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity ATP Binding Signaling Receptor Activity
	Biological Process	Nitric Oxide Biosynthetic Process Nitrate Metabolic Process Detoxification Of Nitrogen Compound Cellular Detoxification Of Nitrogen Compound	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Axon Guidance Peptidyl-tyrosine Phosphorylation Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Kinase Activity Ephrin Receptor Signaling Pathway
Pathways		Phase I - Functionalization of compounds	EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells
Drugs			Fostamatinib
Diseases
GWAS		Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874)	Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576 29875488) Cancer ( 29299148)
Interacting Genes		7 interacting genes: C1orf115 DISP1 EPHB6 HHIPL2 IARS2 NAA11 SLC30A10	27 interacting genes: AFDN ASB12 CBL CRK CRKL DDIT4L DUSP18 DUSP19 EFNB2 EPHB1 ERBB2 GRB2 HDHD2 INCA1 MSX2 MTARC1 NIF3L1 NOTCH2NLA POU6F2 PRMT5 REL SAT1 STYX TCF4 TEKT5 TRIB3 TRIM39
Entrez ID		64757	2051
HPRD ID		08653	04133
Ensembl ID		ENSG00000186205	ENSG00000106123
Uniprot IDs		Q5VT66	F8WCM8 J3KQU5 O15197
PDB IDs		6FW2
Enriched GO Terms of Interacting Partners?
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