PLPPR2 and TMED9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLPPR2	TMED9
Description		phospholipid phosphatase related 2	transmembrane p24 trafficking protein 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Synaptic Vesicle Integral Component Of Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle Trans-Golgi Network Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Exosome
	Molecular Function	Protein Binding Phosphatidate Phosphatase Activity Lipid Phosphatase Activity	Protein Binding Syntaxin Binding
	Biological Process	Phospholipid Metabolic Process Signal Transduction Phospholipid Dephosphorylation	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Positive Regulation Of Organelle Organization Protein Exit From Endoplasmic Reticulum Early Endosome To Golgi Transport COPI Coating Of Golgi Vesicle
Pathways		Lysosphingolipid and LPA receptors	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		21 interacting genes: ARL13B CD79A CIAO2A CISD2 CLDN5 CREB3L1 GYPC KIR2DL3 LYPD5 MARCHF2 SCN3B SIGLEC12 SLC19A3 SMAGP SSMEM1 STX12 TMED9 TMEM237 TMIE UBE2J1 VSIR	14 interacting genes: AQP9 CDC42 CKMT2 COPZ1 DDX54 ITM2A MAT2B MTF2 NMT2 PLPPR2 SEC22A SEC23B THAP8 TMEM60
Entrez ID		64748	54732
HPRD ID		17442	09975
Ensembl ID		ENSG00000105520	ENSG00000184840
Uniprot IDs		A0A024R7E2 Q96GM1	A0A024R7M0 Q9BVK6
PDB IDs
Enriched GO Terms of Interacting Partners?
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