BLVRB and ORM1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		BLVRB	ORM1
Description		biliverdin reductase B	orosomucoid 1
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Terminal Bouton Intracellular Membrane-bounded Organelle Extracellular Exosome	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Specific Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Tertiary Granule Lumen
	Molecular Function	Biliverdin Reductase (NAD(P)+) Activity Protein Binding Riboflavin Reductase (NADPH) Activity Biliberdin Reductase NAD+ Activity Biliverdin Reductase (NADP+) Activity	Protein Binding
	Biological Process	Heme Catabolic Process	Regulation Of Immune System Process Acute-phase Response Inflammatory Response Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production
Pathways		Heme degradation Cytoprotection by HMOX1	Platelet degranulation Neutrophil degranulation
Drugs		Riboflavin NADH Biliverdine IX Alpha Flavin mononucleotide Nicotinamide adenine dinucleotide phosphate Lumichrome Mesobiliverdin IV alpha	Amsacrine Lidocaine Progesterone Chlorpromazine Dipyridamole Thalidomide
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	End-stage coagulation ( 23381943) Thrombin generation potential phenotypes ( 24357727) Tourette syndrome ( 22889924)
Interacting Genes		4 interacting genes: ANXA10 HMOX1 ORM1 RPL31	9 interacting genes: ALB BLVRB CCR5 GLUD1 GSDMB PIK3R3 SERPINE1 TMEM37 TP63
Entrez ID		645	5004
HPRD ID		02967	00724
Ensembl ID		ENSG00000090013	ENSG00000229314
Uniprot IDs		P30043 V9HWI1	P02763
PDB IDs		1HDO 1HE2 1HE3 1HE4 1HE5 5OOG 5OOH 6OPL	3KQ0
Enriched GO Terms of Interacting Partners?
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