SGK1 and PDK1

  • Number of citations of the paper that reports this interaction (PubMedID 17314099)
  • 27
  • Data Source:
  • BioGRID (enzymatic study)

SGK1

PDK1

Description serum/glucocorticoid regulated kinase 1 pyruvate dehydrogenase kinase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blond vs. brown/black hair color ( 30531825)
  • Body mass index (smoking years interaction) ( 23192594)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
  • Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio) ( 33987465)
  • Pelvic organ prolapse ( 26545240)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • Refractive error ( 32231278)
  • Schizophrenia (inflammation and infection response interaction) ( 25781172)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Blood protein levels ( 28240269)
  • Erectile dysfunction in type 1 diabetes ( 22704111)
  • Fasting plasma glucose ( 25187374)
Interacting Genes 37 interacting genes: ASPG BRAF CAMKK1 CARHSP1 CDKN1B CETN3 CREB1 FANCA FOXO3 GADD45G GSK3A GSK3B IKBKG KCNJ1 KPNA2 MAGEA1 MAL2 MAPK7 MAPKAP1 MLLT3 NDRG1 NDRG4 NEDD4 NEDD4L NEK6 PDK1 PDK2 PDPK1 PIK3CA PIN1 PPP2CA RABAC1 RICTOR SLC1A3 SLC9A3R2 TMEM184C UBC 15 interacting genes: AKT1 COL6A1 DLAT FGFR1 ITGB3 KAT2B LAMTOR5 PDHA1 PDK2 PIK3CA RPS6KB1 SGK1 USP4 XRCC6 YWHAQ
Entrez ID 6446 5163
HPRD ID 04264 03954
Ensembl ID ENSG00000118515 ENSG00000152256
Uniprot IDs B7Z325 E9PR89 O00141 B7Z7N6 Q15118
PDB IDs 2R5T 3HDM 3HDN 2Q8F 2Q8G 2Q8H
Enriched GO Terms of Interacting Partners?
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