HERPUD2 and UBE2B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HERPUD2	UBE2B
Description		HERPUD family member 2	ubiquitin conjugating enzyme E2 B
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GO Annotations	Cellular Component	Integral Component Of Membrane	Chromatin XY Body Nucleus Nucleoplasm Replication Fork Cytoplasm Plasma Membrane HULC Complex
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Spermatogenesis Endoplasmic Reticulum Unfolded Protein Response	Protein Polyubiquitination In Utero Embryonic Development DNA Repair Postreplication Repair Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Spermatogenesis Sperm Axoneme Assembly Response To Xenobiotic Stimulus Response To UV Positive Regulation Of Reciprocal Meiotic Recombination Protein Ubiquitination Histone Ubiquitination Negative Regulation Of Histone Phosphorylation Histone H2A Ubiquitination Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of CAMP-mediated Signaling Meiotic Telomere Clustering Protein Stabilization Chiasma Assembly Protein Autoubiquitination Histone Lysine Demethylation Synaptonemal Complex Organization Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways			Recognition of DNA damage by PCNA-containing replication complex Synthesis of active ubiquitin: roles of E1 and E2 enzymes E3 ubiquitin ligases ubiquitinate target proteins Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cognitive function ( 24684796) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Essential hypertension (time to event) ( 32589924) Obesity-related traits ( 23251661) PR interval ( 30679814 30046033 32439900)	Relative amplitude of rest-activity cycles ( 30120083)
Interacting Genes		16 interacting genes: ALG10 CYB561A3 EFNA5 IER3IP1 MS4A13 NAF1 SLC35A4 SLC39A9 SLC7A1 SPTSSA TAS2R10 TMBIM6 TMEM144 TMEM31 TMEM60 UBE2B	26 interacting genes: BIRC2 CBX5 CDKN1B CNOT4 CRMP1 CTNNB1 FBN2 H2AC20 HERPUD2 MED31 PCNA PRKN RAD18 RC3H1 RC3H2 RNF20 RNF4 RNF40 TRIM14 TRIM45 UBA1 UBR1 UBR2 UBR3 UBR5 UNC119
Entrez ID		64224	7320
HPRD ID		07984	01533
Ensembl ID		ENSG00000122557	ENSG00000119048
Uniprot IDs		A0A024RA77 Q9BSE4	P63146
PDB IDs		2KDB	1JAS 1NXA 2Y4W 2YB6 2YBF
Enriched GO Terms of Interacting Partners?
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