IRF2BPL and UBE2Q1

Number of citations of the paper that reports this interaction (PubMedID 19690564)
64

Data Source:
BioGRID (two hybrid)

		IRF2BPL	UBE2Q1
Description		interferon regulatory factor 2 binding protein like	ubiquitin conjugating enzyme E2 Q1
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm	Nucleus Cytosol Filopodium
	Molecular Function	Transcription Corepressor Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Nervous System Development Protein Ubiquitination Positive Regulation Of Transcription By RNA Polymerase II Development Of Secondary Female Sexual Characteristics	Protein Polyubiquitination Suckling Behavior Embryo Implantation Mating Behavior Fertilization Reproductive System Development Prolactin Secretion
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998) Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Atrial fibrillation ( 30061737 29892015) Feeling nervous ( 29500382) Paclitaxel disposition in epithelial ovarian cancer ( 29367611)	Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798)
Interacting Genes		3 interacting genes: FGFR3 HCK UBE2Q1	13 interacting genes: ECPAS FHL3 IRF2BPL ITCH LMNA MDM2 OGT RNF26 RNF31 RNF7 STUB1 TP53 UBC
Entrez ID		64207	55585
HPRD ID		10713	15601
Ensembl ID		ENSG00000119669	ENSG00000160714
Uniprot IDs		Q9H1B7	Q7Z7E8
PDB IDs		2B9G 2CS3	2QGX
Enriched GO Terms of Interacting Partners?
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