LIN7B and ASIC3

Number of citations of the paper that reports this interaction (PubMedID 15317815)
30

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (two hybrid, in vivo)

		LIN7B	ASIC3
Description		lin-7 homolog B, crumbs cell polarity complex component	acid sensing ion channel subunit 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Basolateral Plasma Membrane Synapse MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane	Plasma Membrane Integral Component Of Plasma Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Protein Domain Specific Binding PDZ Domain Binding L27 Domain Binding	Cation Channel Activity Sodium Channel Activity Ligand-gated Sodium Channel Activity Enterobactin Transmembrane Transporter Activity Acid-sensing Ion Channel Activity
	Biological Process	Exocytosis Neurotransmitter Secretion Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Basolateral Plasma Membrane	Signal Transduction Sensory Perception Response To Heat Response To Acidic PH Sodium Ion Transmembrane Transport Enterobactin Transport Sensory Perception Of Sour Taste Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain
Pathways		Dopamine Neurotransmitter Release Cycle RHO GTPases Activate Rhotekin and Rhophilins Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors	Stimuli-sensing channels
Drugs			Agmatine
Diseases
GWAS			Eyebrow thickness ( 26926045)
Interacting Genes		23 interacting genes: ABCA1 APBA1 ASIC3 BAIAP2 CASK DLG4 DNAH1 ENKD1 GNG13 GRIK2 GRIN2B KCNJ12 KCNJ4 MAK16 MPP2 MPP3 MPP7 NTAQ1 PALS1 PALS2 PSMB1 TCEANC TRAPPC12	9 interacting genes: ASIC2 CSNK2A1 DLG4 GOPC LIN7B MAGI1 PATJ PRKACA STOM
Entrez ID		64130	9311
HPRD ID		10040	10626
Ensembl ID		ENSG00000104863	ENSG00000213199
Uniprot IDs		Q9HAP6	A0A090N7X8 A0A090N8Q1 A0A090N8Z6 Q9UHC3
PDB IDs		2DKR
Enriched GO Terms of Interacting Partners?
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