CXCL12 and CCL28

  • Number of citations of the paper that reports this interaction (PubMedID 28381538)
  • 37

CXCL12

CCL28

Description C-X-C motif chemokine ligand 12 C-C motif chemokine ligand 28
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anti-drug antibodies in autoimmune disease (time to event) ( 33125391)
  • Blood protein levels ( 30072576)
  • Body mass index ( 25760438)
  • Coronary artery disease ( 32469254 26708285 24262325 26343387)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 17634449 21378990)
  • Diastolic blood pressure ( 27841878)
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of white cells ( 32888494)
  • Granulocyte count ( 27863252)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676)
  • Lymphocyte counts ( 32888494)
  • Monocyte count ( 32888494 27863252)
  • Myeloid white cell count ( 27863252)
  • Myocardial infarction ( 33532862 26343387)
  • Myocardial infarction (early onset) ( 19198609)
  • Neutrophil count ( 32888494 27863252)
  • QT interval (ambient particulate matter interaction) ( 28749367)
  • Red blood cell count ( 32888494)
  • Resistance to Mycobacterium tuberculosis in HIV-positive individuals measured by a negative tuberculin skin test (continuous) ( 28628665)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
  • Schizophrenia ( 23212062)
  • Smoking initiation (ever regular vs never regular) ( 31089300)
  • Sum basophil neutrophil counts ( 27863252)
  • Sum neutrophil eosinophil counts ( 27863252)
  • White blood cell count ( 32888494 27863252)
  • Metabolite levels (X-11787) ( 23934736)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes 32 interacting genes: CCL11 CCL13 CCL20 CCL21 CCL25 CCL26 CCL28 CCL5 CD4 CTSG CXCL10 CXCL11 CXCL14 CXCL17 CXCL2 CXCL6 CXCL9 CXCR4 DAZAP2 DPP4 ELANE FBXO7 FN1 MMP2 NIF3L1 PF4 PF4V1 PPBP RPS6KA1 VCAN XCL1 XCL2 26 interacting genes: ACKR2 CCL11 CCL13 CCL17 CCL21 CCL26 CCL5 CCR10 CCR3 CXCL10 CXCL12 CXCL13 CXCL14 CXCL17 CXCL2 CXCL9 DDI1 DYNLT3 PF4 PF4V1 PPBP PSMA3 STUB1 TSC1 XCL1 XCL2
Entrez ID 6387 56477
HPRD ID 02904 05577
Ensembl ID ENSG00000107562 ENSG00000151882
Uniprot IDs P48061 A0N0Q3 D6RC73 Q9NRJ3
PDB IDs 1A15 1QG7 1SDF 1VMC 2J7Z 2K01 2K03 2K04 2K05 2KEC 2KED 2KEE 2KOL 2N55 2NWG 2SDF 3GV3 3HP3 4LMQ 4UAI 6SHR 6CWS
Enriched GO Terms of Interacting Partners?
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