BIK and EXOC3L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BIK	EXOC3L2
Description		BCL2 interacting killer	exocyst complex component 3 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Endomembrane System Integral Component Of Membrane Mitochondrial Membrane	Exocyst Cellular_component
	Molecular Function	Protein Binding	SNARE Binding Molecular_function Protein Binding
	Biological Process	Apoptotic Process Male Gonad Development Apoptotic Mitochondrial Changes Positive Regulation Of Protein-containing Complex Assembly Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria	Exocytosis Biological_process Exocyst Localization
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 25939597 21743057) Prostate cancer (SNP x SNP interaction) ( 22219177)	Advanced age-related macular degeneration ( 26691988) Alzheimer's disease ( 24755620) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Coronary artery disease ( 29212778) Heel bone mineral density ( 30598549) Hemoglobin ( 32888494) Mean platelet volume ( 32888494 27863252) Parental longevity (father's attained age) ( 29227965) Platelet count ( 22139419 32888494) Platelet distribution width ( 32888494) Red blood cell count ( 32888494) Serum uric acid levels ( 29559957) White blood cell count ( 32888494)
Interacting Genes		94 interacting genes: ADGRE2 ADIPOQ AIG1 ALG8 ANKRD46 APOD APP ASB11 BCL2 BCL2A1 BCL2L1 BCL2L10 BCL2L2 BMP10 BNIP3 BRICD5 BTN2A2 C14orf180 C3orf52 C4orf3 CD53 CD72 CLDN19 CMTM5 CMTM7 CNIH1 CNIH3 CREB3 CRKL CTXN3 CXCL16 CYB561 CYB5B ELOVL4 ERGIC3 EXOC3L2 FAM209A FAM241B FAM3C FATE1 FCGR1A GPX8 GRM2 INSIG2 KCNN4 MARCHF5 MCL1 MS4A13 NAT8 NR2F2 NRM PBX3 PGAP2 PGRMC1 PLN PLP1 PLP2 PLPP4 REEP4 RUSF1 S100A1 SCAMP4 SEC22A SELENOK SERP1 SERP2 SLC35E3 SLC37A4 SLC39A7 SMIM1 SOCS3 STRIT1 STX8 TANK TMBIM1 TMEM107 TMEM11 TMEM14B TMEM14C TMEM199 TMEM222 TMEM229B TMEM243 TMEM254 TMEM60 TMEM80 TMEM86B TMEM97 TRARG1 TSPO2 UBIAD1 VAMP3 VAMP5 ZFPL1	7 interacting genes: BIK GAGE12G GAGE2E GPR148 MRPL12 ODAD1 TNFSF18
Entrez ID		638	90332
HPRD ID		04547	10311
Ensembl ID		ENSG00000100290	ENSG00000283632
Uniprot IDs		A0A024R4X6 Q13323	Q2M3D2
PDB IDs		2IPE
Enriched GO Terms of Interacting Partners?
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